Department of Physiology, Shri B.M.Patil Medical College, Hospital and Research Centre, BLDE (Deemed to be University), Vijayapura, Karnataka, India.
Department of Biochemistry, Shri B.M.Patil Medical College, Hospital and Research Centre, BLDE (Deemed to be University), Vijayapura, Karnataka, India.
Complement Ther Clin Pract. 2019 Feb;34:288-293. doi: 10.1016/j.ctcp.2019.01.003. Epub 2019 Jan 8.
The present study was aimed to determine the effect of yoga program on cardiac autonomic dysfunction and insulin resistance in non-diabetic offspring of diabetes parents.
A randomized passive-controlled study was conducted on 64 non-diabetic offspring of type-2-diabetes parents (mean-age:25.17years). Yoga group participants received yoga training for 8 weeks. Heart-rate variability (HRV) indices: low frequency (LF), high frequency (HF) and LF/HF ratio; fasting blood glucose (FBG), oral glucose tolerance test (OGTT) and insulin resistance (IR) were estimated at baseline and after 8-weeks of intervention.
We found a significant decrease in LF (p = 0.005), LF/HF ratio (p = 0.004), IR (p < 0.001), OGTT (p = 0.003) and increase in HF (p = 0.022) in yoga group participants. Control group participants did not show any significant change in any variables.
Improvement in cardiac autonomic function and insulin resistance by yoga training implies that yoga can reduce the risk of development of diabetes in offspring of diabetes parents.
本研究旨在探讨瑜伽方案对 2 型糖尿病父母非糖尿病子女心脏自主神经功能障碍和胰岛素抵抗的影响。
采用随机被动对照研究，纳入 64 名 2 型糖尿病父母的非糖尿病子女（平均年龄：25.17 岁）。瑜伽组参与者接受 8 周的瑜伽训练。在基线和干预 8 周后，评估心率变异性（HRV）指数：低频（LF）、高频（HF）和 LF/HF 比值；空腹血糖（FBG）、口服葡萄糖耐量试验（OGTT）和胰岛素抵抗（IR）。
我们发现瑜伽组参与者的 LF（p=0.005）、LF/HF 比值（p=0.004）、IR（p<0.001）、OGTT（p=0.003）显著降低，HF（p=0.022）显著升高。对照组参与者的任何变量均无显著变化。
瑜伽训练改善心脏自主神经功能和胰岛素抵抗，提示瑜伽可能降低 2 型糖尿病父母非糖尿病子女发生糖尿病的风险。
