Infectious Diseases and Medical Microbiology McGill University Health Centre, 1001, Boul Decarie Bloc E, E05.1616, Montreal, Quebec H4A3J1, Canada.
Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Office 200, 150 Place Charles-Le Moyne, Longueuil, Québec J4K 0A8, Canada.
Infect Dis Clin North Am. 2019 Mar;33(1):231-245. doi: 10.1016/j.idc.2018.10.009.
Antimicrobial resistance (AMR) is on the rise and spreading rapidly worldwide. Low- and middle-income countries, because of weak health systems, are particularly vulnerable to this increase. Population mobility further fuels the globalization of AMR, with travelers and migrants at significant risk of harboring drug-resistant organisms. This article provides an overview of the factors that contribute to the emergence, spread, and persistence of AMR, particularly antibiotic-resistance, in the tropics. Also addressed are clinical implications of this emergent global crisis for migrants and travelers, using specific scenarios commonly encountered in those populations.
抗微生物药物耐药性(AMR)正在上升并在全球范围内迅速传播。由于卫生系统薄弱,低收入和中等收入国家特别容易受到这种增加的影响。人口流动进一步推动了 AMR 的全球化,旅行者和移民携带耐药生物体的风险显著增加。本文概述了导致热带地区 AMR(特别是抗生素耐药性)出现、传播和持续存在的因素。还讨论了这种新兴的全球危机对移民和旅行者的临床影响,使用了这些人群中常见的具体情况。