Intensive Care Unit, Polyclinique Bordeaux Nord Aquitaine, 15 rue Claude Boucher, Bordeaux 33000, France; Intensive Care Unit, Mamoudzou Hospital, rue de l'Hôpital, Mayotte 97600, France.
Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada; Interdepartmental Division of Critical Care, University of Toronto, 209 Victoria Street, 4th Floor, Room 411, Toronto, Ontario M5B 1T8, Canada.
Infect Dis Clin North Am. 2019 Mar;33(1):247-264. doi: 10.1016/j.idc.2018.10.013.
The 2014 to 2016 Ebola virus disease outbreak underscored the threat posed by hemorrhagic fevers. Filoviral outbreaks have been identified since 1967, but data collection has remained sparse, limiting current knowledge of these illnesses. Documentation of objective physical signs and laboratory parameters and appropriate clinical management are connected and interdependent. Implementing both is necessary to improve outcomes. Clinical features include severe volume depletion due to diarrhea and vomiting, shock, rhabdomyolysis, and metabolic disturbances. Overt hemorrhage is uncommon. Point-of-care devices and inexpensive electronic equipment enable better monitoring and record keeping in resource-limited settings.
2014 年至 2016 年的埃博拉病毒病疫情凸显了出血热带来的威胁。自 1967 年以来，已发现丝状病毒暴发，但数据收集仍然很少，限制了目前对这些疾病的了解。客观的身体体征和实验室参数的记录以及适当的临床管理是相互关联和相互依存的。实施这两者对于改善结果都是必要的。临床特征包括腹泻和呕吐导致的严重容量耗竭、休克、横纹肌溶解和代谢紊乱。明显的出血并不常见。即时检测设备和廉价的电子设备使资源有限的环境中能够更好地进行监测和记录。
