Chan T C Y, Chow S S W, Wan K H N, Yuen H K L
Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong.
Hong Kong Sanatorium & Hospital, Happy Valley, Hong Kong.
Hong Kong Med J. 2019 Feb;25(1):38-47. doi: 10.12809/hkmj187331. Epub 2019 Jan 31.
Dry eye disease is one of the most common ophthalmic complaints; it results from the activity of various pathways and is considered a multifactorial disease. An important factor that contributes to the onset of dry eye disease is meibomian gland dysfunction. Meibomian gland dysfunction causes a disruption in the tear film lipid layer which affects the rate of tear evaporation. This evaporation leads to tear hyperosmolarity, eventually triggering the onset of dry eye disease. Dry eye disease and meibomian gland dysfunction are strongly associated with each other, such that many of their risk factors, signs, and symptoms overlap. This review aimed to provide an update on the association between dry eye disease and meibomian gland dysfunction. A stepwise approach for diagnosis and management is summarised.
干眼症是最常见的眼科病症之一；它由多种途径的活动引起，被认为是一种多因素疾病。睑板腺功能障碍是导致干眼症发病的一个重要因素。睑板腺功能障碍会导致泪膜脂质层破坏，从而影响泪液蒸发速率。这种蒸发会导致泪液高渗，最终引发干眼症。干眼症和睑板腺功能障碍彼此密切相关，以至于它们的许多危险因素、体征和症状相互重叠。本综述旨在提供有关干眼症与睑板腺功能障碍之间关联的最新信息。总结了一种逐步的诊断和管理方法。
