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维罗纳医院急诊科中惊恐发作(PA)和惊恐障碍(PD)患者的患病率。

The Prevalence of patients with panic attacks (PAs) and panic disorder (PD) visiting Emergency Departments of the Verona Hospital.

作者信息

Majori S, Gazzani D, Paiano J, Carobolante B, Sannino A, Ferrari S, Antolini L, Aprili I, Zanon M

机构信息

Department of Public Health and Community Medicine, Hygiene and Environmental Occupational Preventive Medicine Division, University of Verona, Italy.

Specialization School in Hygiene and Preventive Medicine, University of Verona, Italy.

出版信息

Ann Ig. 2019 Mar-Apr;31(2):93-108. doi: 10.7416/ai.2019.2262.

Abstract

BACKGROUND

Panic Attacks (PAs) and Panic Disorder (PD) represent a heavy burden not only because of the difficulty in distinguishing them from other pathologies and in treating them appropriately but also because of their impact on public health worldwide. In Europe, PD constitutes one of the five most common mental disorders adversely affecting quality of life.

STUDY DESIGN

The aim of this study is to evaluate the period prevalence of visits to the Emergency Departments of the University Hospital of Verona (North East of Italy) over the period between 2012-2016 because of symptoms of PAs or PD in order to quantify the burden of the disorder.

METHODS

This study was carried out by retrospectively collecting data from the medical records of all the patients assessed at the Emergency Departments (EDs) of the Verona Hospital because of symptoms of PAs or PD over a 5-year period (1 January 2012 - 31 December 2016). The search words used in reviewing the medical records registered in the hospital discharge reports from the Gynecological, Pediatric and General Medicine Emergency Departments were: "Anxiety" and/or "Panic". A multiple logistic regression model was also created to evaluate the predictors of ED visits for PAs or PD over the period that was investigated.

RESULTS

The study identified 3,771 cases of PAs or PD; 62.3% were females and 37.7% were males. The female-to-male ratio was 1.7:1. The mean age was 44 years (46 for the females and 41 for the males). The majority of the patients fell into two age categories: 30 to 39 (20.6%) and 40 to 49 (23.8%). The proportion of visits to the EDs for PAs or PD was approximately 20% per year, with an average of approximately 754 patients visiting the EDs every year. The period prevalence of accesses for PAs or PD over the five year period studied in the mean resident population (1.4%) and the mean visits to the EDs (2.5%) were calculated. Study results showed that the majority of the patients (80.9%) were referred to their general practitioner (GP) at the end of the assessment protocol at the EDs. According to the regression logistic model, the following variables were significant (p<0.05) risk factors for PAs or PD: being female vs. male (OR 1.899; 95% CI 1.785-2.020), being Italian vs. Foreigner (OR 1.292; 95% CI 1.174-1.421), having a white or green priority code at arrival (low urgency) vs. the other ones (OR 1.195; 95% CI 1.100-1.297), and being aged ≤42 years old (OR 1.091; 95% CI 1.024-1.161).

CONCLUSION

The role of the GP is crucial in the management of PD and PAs. Given the difficulty of implementing primary and secondary prevention programs for these conditions, public health officials should make every effort to promote tertiary prevention in order to reduce the burden of the ailment and societal cost.

摘要

背景

惊恐发作(PA)和惊恐障碍(PD)带来了沉重负担,这不仅是因为难以将它们与其他病症区分开来并进行适当治疗,还因为它们对全球公共卫生产生影响。在欧洲,PD是对生活质量产生不利影响的五种最常见精神障碍之一。

研究设计

本研究的目的是评估2012年至2016年期间因PA或PD症状前往维罗纳大学医院(意大利东北部)急诊科就诊的期间患病率,以便量化该疾病的负担。

方法

本研究通过回顾性收集维罗纳医院急诊科在5年期间(2012年1月1日至2016年12月31日)因PA或PD症状接受评估的所有患者的病历数据进行。在审查妇科、儿科和普通内科急诊科医院出院报告中登记的病历时使用的搜索词为:“焦虑”和/或“惊恐”。还创建了一个多元逻辑回归模型,以评估在所研究期间因PA或PD前往急诊科就诊的预测因素。

结果

该研究确定了3771例PA或PD病例;62.3%为女性,37.7%为男性。男女比例为1.7:1。平均年龄为44岁(女性为46岁,男性为41岁)。大多数患者分为两个年龄组:30至39岁(20.6%)和40至49岁(23.8%)。因PA或PD前往急诊科就诊的比例每年约为20%,平均每年约有754名患者前往急诊科就诊。计算了在所研究的五年期间PA或PD就诊的期间患病率(平均常住人口中的患病率为1.4%)以及前往急诊科的平均就诊率(2.5%)。研究结果表明,大多数患者(80.9%)在急诊科评估方案结束时被转诊至其全科医生(GP)处。根据回归逻辑模型,以下变量是PA或PD的显著(p<0.05)危险因素:女性与男性相比(比值比1.899;95%置信区间1.785 - 2.020)、意大利人与外国人相比(比值比1.292;95%置信区间1.174 - 1.421)、到达时拥有白色或绿色优先代码(低紧急程度)与其他代码相比(比值比1.195;95%置信区间1.100 - 1.297)以及年龄≤42岁(比值比1.091;95%置信区间1.024 - 1.161)。

结论

全科医生在PD和PA的管理中起着关键作用。鉴于实施针对这些病症的一级和二级预防计划存在困难,公共卫生官员应尽一切努力促进三级预防,以减轻疾病负担和社会成本。

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