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美国黑人和非裔美国人中暴露前预防药物的空间可及性及使用意愿:横断面调查

Spatial Access and Willingness to Use Pre-Exposure Prophylaxis Among Black/African American Individuals in the United States: Cross-Sectional Survey.

作者信息

Ojikutu Bisola O, Bogart Laura M, Mayer Kenneth H, Stopka Thomas J, Sullivan Patrick S, Ransome Yusuf

机构信息

Department of Medicine, Brigham and Women's Hospital, Division of Global Health Equity, Harvard Medical School, Boston, MA, United States.

RAND Corporation, Santa Monica, CA, United States.

出版信息

JMIR Public Health Surveill. 2019 Feb 4;5(1):e12405. doi: 10.2196/12405.

Abstract

BACKGROUND

Uptake of pre-exposure prophylaxis (PrEP) among black individuals in the United States is low and may be associated with the limited availability of clinics where PrEP is prescribed.

OBJECTIVE

We aimed to determine the association between spatial access to clinics where PrEP is prescribed and willingness to use PrEP.

METHODS

We identified locations of clinics where PrEP is prescribed from AIDSVu.org and calculated the density of PrEP clinics per 10,000 residents according to the ZIP code. Individual-level data were obtained from the 2016 National Survey on HIV in the Black Community. We used multilevel modelling to estimate the association between willingness to use PrEP and clinic density among participants with individual-level (HIV risk, age, gender, education, income, insurance, doctor visit, census region, urban/rural residence) and ZIP code-level (%poverty, %unemployed, %uninsured, %black population, and density of health care facilities) variables.

RESULTS

All participants identified as black/African American. Of the 787 participants, 45% were men and 23% were found to be at high risk based on the self-reported behavioral characteristics. The mean age of the participants was 34 years (SD 9), 54% of participants resided in the South, and 26% were willing to use PrEP. More than one-third (38%) of the sample had to drive more than 1 hour to access a PrEP provider. Participants living in areas with higher PrEP clinic density were significantly more willing to use PrEP (one SD higher density of PrEP clinics per 10,000 population was associated with 16% higher willingness [adjusted prevalence ratio=1.16, 95% CI: 1.03-1.31]).

CONCLUSIONS

Willingness to use PrEP was associated with spatial availability of clinics where providers prescribe PrEP in this nationally representative sample of black African Americans.

摘要

背景

美国黑人中暴露前预防(PrEP)的使用率较低,这可能与开具PrEP处方的诊所数量有限有关。

目的

我们旨在确定获取开具PrEP处方诊所的空间便利性与使用PrEP意愿之间的关联。

方法

我们从AIDSVu.org网站确定了开具PrEP处方诊所的位置,并根据邮政编码计算每10000名居民中PrEP诊所的密度。个体层面的数据来自2016年黑人社区艾滋病毒全国调查。我们使用多水平模型来估计在具有个体层面(艾滋病毒风险、年龄、性别、教育程度,收入、保险、看医生次数、人口普查区域、城乡居住情况)和邮政编码层面(贫困率、失业率、未参保率、黑人人口比例以及医疗保健设施密度)变量的参与者中,使用PrEP的意愿与诊所密度之间的关联。

结果

所有参与者均为黑人/非裔美国人。在787名参与者中,45%为男性,根据自我报告的行为特征,23%被发现处于高风险。参与者的平均年龄为34岁(标准差9),54%的参与者居住在南部,26%愿意使用PrEP。超过三分之一(38%)的样本需要开车1个多小时才能找到提供PrEP的医疗机构。生活在PrEP诊所密度较高地区的参与者使用PrEP的意愿明显更高(每10000人口中PrEP诊所密度每增加一个标准差,使用意愿就会高出16%[调整后的患病率比值=1.16,95%置信区间:1.03 - 1.31])。

结论

在这个具有全国代表性的非洲裔美国黑人样本中,使用PrEP的意愿与开具PrEP处方诊所的空间可及性有关。

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