Department of Biology, Emory University, Atlanta, Georgia, United States of America.
PLoS Biol. 2019 Feb 4;17(2):e3000129. doi: 10.1371/journal.pbio.3000129. eCollection 2019 Feb.
Understanding how microbes adapt to their host is an enduring problem in microbiome ecology, and understanding the microbial traits that allow colonization of the host and increase adaptation to the host environment is of particular interest. In this study, Robinson and colleagues use experimental evolution to demonstrate adaptation of a commensal bacterium to its zebrafish host and describe the changes in phenotype that emerge during this evolutionary process. These results provide insight into the evolutionary problem of host adaptation and demonstrate the utility of simple models for understanding host-microbiome dynamics.
了解微生物如何适应其宿主是微生物组生态学中的一个持久问题,而了解允许微生物定植宿主并增加对宿主环境适应的微生物特征则特别有趣。在这项研究中,Robinson 及其同事使用实验进化来证明一种共生细菌对其斑马鱼宿主的适应性,并描述了在这个进化过程中出现的表型变化。这些结果为宿主适应的进化问题提供了深入了解,并展示了简单模型在理解宿主-微生物组动态方面的实用性。