Snipelisky David, Chaudhry Sunit-Preet, Stewart Garrick C
Division of Cardiovascular Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
Advanced Heart Failure and Transplant, St. Vincent Heart Center, 8333 Naab Road, Indianapolis, IN 46260, USA.
Card Electrophysiol Clin. 2019 Mar;11(1):11-20. doi: 10.1016/j.ccep.2018.11.001. Epub 2018 Dec 24.
Heart failure is a heterogeneous clinical syndrome stemming from cardiac overload and injury that leads to considerable morbidity and mortality. This review highlights the many faces of heart failure, a major and growing public health problem, including its causes, classification, underlying pathophysiology, and variable progression. An individualized, patient-centered treatment approach that focuses on guideline-directed pharmacologic and device therapies is required for optimal management of this complex syndrome.
心力衰竭是一种异质性临床综合征，源于心脏负荷过重和损伤，可导致相当高的发病率和死亡率。本综述重点介绍了心力衰竭这一重大且日益严重的公共卫生问题的诸多方面，包括其病因、分类、潜在病理生理学以及不同的进展情况。对于这一复杂综合征的最佳管理，需要一种以患者为中心的个体化治疗方法，该方法侧重于遵循指南的药物和器械治疗。
