Tayal Bhupendar, Sogaard Peter, Risum Niels
Department of Cardiology, Aalborg University Hospital, Hobrovej 18-22, Aalborg 9100, Denmark.
Department of Cardiology, Aalborg University Hospital, Hobrovej 18-22, Aalborg 9100, Denmark.
Card Electrophysiol Clin. 2019 Mar;11(1):39-47. doi: 10.1016/j.ccep.2018.11.006. Epub 2018 Dec 24.
Cardiac resynchronization therapy (CRT) is an electrical therapy to resolve an electrical problem. Any method to predict CRT response must specifically reflect the electrical substrate. Time-to-peak dyssynchrony is too unspecific for prediction of response because dyssynchrony by this approach may reflect the presence of scar or fibrosis even in the absence of conduction delay. New methods are based on the actual physiology of activation delay-induced heart failure (HF) and are superior to time-to-peak methods in predicting CRT response. Time-to-peak dyssynchrony may be used for prognosis in HF patients without signs of delayed ventricular activation and for monitoring CRT response.
心脏再同步治疗（CRT）是一种解决电问题的电疗法。任何预测CRT反应的方法都必须具体反映电基质。达到峰值不同步的时间对于预测反应来说过于不具特异性，因为通过这种方法出现的不同步可能即使在没有传导延迟的情况下也反映了瘢痕或纤维化的存在。新方法基于激活延迟诱发心力衰竭（HF）的实际生理学，在预测CRT反应方面优于达到峰值的方法。达到峰值不同步的时间可用于无心室激活延迟迹象的HF患者的预后评估以及监测CRT反应。
