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左心室舒张功能障碍的病理生理学和超声心动图诊断。

Pathophysiology and Echocardiographic Diagnosis of Left Ventricular Diastolic Dysfunction.

机构信息

Icahn School of Medicine at Mount Sinai, New York, New York.

出版信息

J Am Soc Echocardiogr. 2019 Feb;32(2):216-232.e2. doi: 10.1016/j.echo.2018.11.011.

DOI:10.1016/j.echo.2018.11.011
PMID:30717860
Abstract

Echocardiography is the primary imaging modality used for the clinical evaluation of left ventricular (LV) diastolic function. Using two-dimensional together with transmitral, mitral annular, and pulmonary venous Doppler data, conclusions may be drawn regarding the relaxation and compliance properties of the ventricle that can be used for estimating LV filling pressure. Echocardiographic estimation of LV filling pressure has been shown to be especially useful for evaluating patients with dyspnea of unknown etiology as well as those with heart failure with preserved ejection fraction. Moreover, echocardiographic estimation of LV filling pressure can be used for clinical decision making on day-to-day basis. This article discusses the pathophysiology of diastolic dysfunction and provides a comprehensive review of its echocardiographic evaluation.

摘要

超声心动图是用于临床评估左心室(LV)舒张功能的主要成像方式。通过二维超声心动图联合经二尖瓣、二尖瓣环和肺静脉多普勒数据,可以得出关于心室弛豫和顺应性的结论,从而用于估计 LV 充盈压。超声心动图估计 LV 充盈压在评估不明原因呼吸困难和射血分数保留的心力衰竭患者方面特别有用。此外,超声心动图估计 LV 充盈压可用于日常临床决策。本文讨论了舒张功能障碍的病理生理学,并对其超声心动图评估进行了全面回顾。

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