Rezaeian Ahmad, Hashemi Seyed Mostafa, Dokhanchi Zeinab Sadat
Department of Otorhinolaryngology, Head and Neck Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Allergy Rhinol (Providence). 2019 Jan 23;10:2152656718821282. doi: 10.1177/2152656718821282. eCollection 2019 Jan-Dec.
Postoperative pain is one of the most complications in endoscopic sinus surgery. We aimed to evaluate the effect of the sphenopalatine ganglion block (SPGB) with bupivacaine on postoperative pain in patients undergoing endoscopic sinus surgery. In this clinical trial, 40 patients who indicated functional endoscopic sinus surgery were selected and then divided into 2 parallel groups as intervention and control. The intervention group was received 1.5 mL of bupivacaine 0.5% (injected to sphenopalatine ganglion) and while control was injected 1.5 mL of normal saline at the same injection site. Also, the visual analogue scale (VAS) was recorded immediately after anesthesia, along with 6, 12, 24, 48 h, 7 days, and 21 days after the operation for all patients.
Immediately after anesthesia, as well as 6, 12, and 24 h after the operation, VAS in the intervention group was significantly lower than in the control group ( < .05, for all). However, there were no significant differences between the 2 groups regarding VAS 48 h as well as 7 and 21 days after surgery ( > .05, for both). Also, the rescue analgesia in the intervention group was significantly lower than in the control group ( = .01).
SPGB with bupivacaine 0.5% (1.5 mL) was a simple, effective, safe, and noninvasive method for the management of postoperative pain in the patients undergoing endoscopic sinus surgery.
术后疼痛是鼻内镜鼻窦手术最常见的并发症之一。我们旨在评估布比卡因翼腭神经节阻滞（SPGB）对接受鼻内镜鼻窦手术患者术后疼痛的影响。在这项临床试验中，选取40例拟行功能性鼻内镜鼻窦手术的患者，然后分为干预组和对照组两个平行组。干预组接受1.5 mL 0.5%布比卡因（注射至翼腭神经节），而对照组在相同注射部位注射1.5 mL生理盐水。此外，所有患者在麻醉后即刻以及术后6、12、24小时、48小时、7天和21天记录视觉模拟评分（VAS）。
麻醉后即刻以及术后6、12和24小时，干预组的VAS显著低于对照组（均P<0.05）。然而，两组在术后48小时以及术后7天和21天的VAS无显著差异（均P>0.05）。此外，干预组的补救性镇痛显著低于对照组（P = 0.01）。
0.5%布比卡因（1.5 mL）的SPGB是一种用于管理接受鼻内镜鼻窦手术患者术后疼痛的简单、有效、安全且无创的方法。
