Zuccolotto Tatiana, Bressan Jaqueline, Lourenço Allan V F, Bruginski Estevan, Veiga Andressa, Marinho Jane V N, Raeski Paola A, Heiden Gustavo, Salvador Marcos J, Murakami Fabio S, Budel Jane M, Campos Francinete R
Departamento de Farmácia, Universidade Federal do Paraná (UFPR), Av. Pref. Lothário Meissner, 632, Jardim Botânico, 80210-170, Curitiba, PR, Brasil.
Departamento de Biologia Vegetal, Instituto de Biologia, Universidade Estadual de Campinas (Unicamp), Barão Geraldo, 13083-971, Campinas, SP, Brasil.
Chem Biodivers. 2019 Apr;16(4):e1800547. doi: 10.1002/cbdv.201800547. Epub 2019 Apr 2.
The aim of this study was to evaluate the chemical, antioxidant, and antimicrobial activity of the essential oils as well as the anatomy of the aerial parts from Baccharis aracatubaensis, Baccharis burchellii, and Baccharis organensis owing to the therapeutic potential of Baccharis. The volatile constituents were analyzed using GC/MS, the antioxidant activity was evaluated by oxygen radical absorbance capacity (ORAC ) and DPPH assays, and the antimicrobial activity by a microdilution technique. Of the 56 compounds identified, only seven (β-caryophyllene, γ-muurolene, bicyclogermacrene, β-germacrene, spathulenol, τ-muurolol, and α-cadinol) were common in the three specimens studied. Of these, γ-muurolene was found abundantly in B. aracatubaensis, while bicyclogermacrene was abundant in B. burchellii and B. organensis. The essential oils exhibited antioxidant activity in the ORAC (>500.0 μmol TE g ) and DPPH assays. However, they did not exhibit any antimicrobial activity. Secretory ducts and flagelliform glandular trichomes were observed in the anatomical study of all the Baccharis species studied.
鉴于白苞蒿属植物的治疗潜力，本研究旨在评估白苞蒿、布氏白苞蒿和奥氏白苞蒿精油的化学、抗氧化和抗菌活性以及地上部分的解剖结构。使用气相色谱/质谱联用仪分析挥发性成分，通过氧自由基吸收能力（ORAC）和DPPH试验评估抗氧化活性，并采用微量稀释技术评估抗菌活性。在所鉴定的56种化合物中，只有7种（β-石竹烯、γ-依兰油烯、双环大根香叶烯、β-大根香叶烯、匙叶桉油烯醇、τ-依兰油醇和α-杜松醇）在所有3个研究样本中都存在。其中，γ-依兰油烯在白苞蒿中含量丰富，而双环大根香叶烯在布氏白苞蒿和奥氏白苞蒿中含量丰富。精油在ORAC（>500.0 μmol TE g）和DPPH试验中表现出抗氧化活性。然而，它们没有表现出任何抗菌活性。在对白苞蒿属所有研究物种的解剖学研究中均观察到分泌道和鞭状腺毛。
