Huynh Van-Anh N, To Quyen G, Do Dung V, Nguyen Mai Th, To Kien G
a Faculty of Public Health , University of Medicine and Pharmacy , Ho Chi Minh City , Vietnam.
b School of Exercise and Nutrition Sciences, Queensland University of Technology , Brisbane , Australia.
AIDS Care. 2019 May;31(5):582-588. doi: 10.1080/09540121.2019.1576846. Epub 2019 Feb 5.
This study investigated correlates of quality of life (QOL) among people living with HIV/AIDS (PLWH) at An Hoa Clinic, Ho Chi Minh City, Vietnam. Inclusive criteria were PLWH ≥18 years old, under antiretroviral therapy (ART) for ≥3 months, and consent to participate. PLWH who were illiterate, too ill, or at the final stage of AIDS were excluded. QOL was assessed using WHOQOL-BREF-HIV. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale. For every point increased in depression score, QOL decreased 0.13 points in Physical (p < .001), 0.12 points in Psychological and Social Relationships (p < .001), 0.07 points in Level of Independence (p < .001), 0.09 points in Environment (p < .001), and 0.15 points in Personal Beliefs domain (p < .001). PLWH from an economically disadvantaged household had lower QOL scores for all QOL domains but Personal Beliefs with differences ranging from 0.81 points for Social Relationships to 1.77 points for Environment domain. PLWH with a co-morbidity had lower scores whereas those living with a spouse and adhering to ART medication had higher scores in at least one QOL domain. In conclusion, depressive symptoms, household economy, living with a spouse, having a co-morbidity and ART medication adherence were important factors associated with PLWH's QOL.
本研究调查了越南胡志明市安和诊所的艾滋病毒/艾滋病患者（PLWH）的生活质量（QOL）相关因素。纳入标准为年龄≥18岁的PLWH，接受抗逆转录病毒治疗（ART）≥3个月，并同意参与。文盲、病情过重或处于艾滋病终末期的PLWH被排除。使用世界卫生组织生活质量简表-艾滋病毒（WHOQOL-BREF-HIV）评估生活质量。使用流行病学研究中心抑郁量表评估抑郁症状。抑郁评分每增加1分，身体领域的生活质量下降0.13分（p <.001），心理和社会关系领域下降0.12分（p <.001），独立水平领域下降0.07分（p <.001），环境领域下降0.09分（p <.001），个人信念领域下降0.15分（p <.001）。来自经济弱势家庭的PLWH在所有生活质量领域（除个人信念外）的得分较低，社会关系领域的差异为0.81分，环境领域为1.77分。患有合并症的PLWH得分较低，而与配偶同住且坚持服用抗逆转录病毒药物的PLWH在至少一个生活质量领域得分较高。总之，抑郁症状、家庭经济状况、与配偶同住、患有合并症以及抗逆转录病毒药物依从性是与PLWH生活质量相关的重要因素。
