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一锅法合成具有增强的催化和等离子体性能的 Cu/Au/Pt 三元金属纳米粒子,作为用于生物传感和癌症治疗的通用平台。

One-pot synthesized Cu/Au/Pt trimetallic nanoparticles with enhanced catalytic and plasmonic properties as a universal platform for biosensing and cancer theranostics.

机构信息

State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Hunan University, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Changsha, Hunan 410082, China.

出版信息

Chem Commun (Camb). 2019 Feb 19;55(16):2321-2324. doi: 10.1039/c8cc10127b.

DOI:10.1039/c8cc10127b
PMID:30720028
Abstract

Cu/Au/Pt trimetallic nanoparticles (TMNPs) with enhanced catalytic activity and intense plasmonic absorption in the NIR-I biowindow (650-950 nm) were prepared using a fast, gentle and one-pot protocol. Based on these properties and assembly of thiolated-aptamers on Cu/Au/Pt TMNPs, a universal platform was developed for applications in biosensing and theranostics.

摘要

采用快速、温和的一锅法制备了具有增强的催化活性和在近红外-I 生物窗口(650-950nm)强等离子体吸收的 Cu/Au/Pt 三金属纳米粒子(TMNPs)。基于这些特性和巯基化适体在 Cu/Au/PtTMNPs 上的组装,开发了一种通用平台,用于生物传感和治疗应用。

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