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1
Prostasomes are Pluripotent and Well-Organized Organelles in Human Semen.前列腺小体是人类精液中具有多能性且结构良好的细胞器。
EJIFCC. 1999 May 29;11(1):1-5. eCollection 1999 May.
2
Prostasome-like granules from the PC-3 prostate cancer cell line increase the motility of washed human spermatozoa and adhere to the sperm.来自PC-3前列腺癌细胞系的前列腺小体样颗粒可提高洗涤后的人类精子的活力，并黏附于精子上。
Eur J Obstet Gynecol Reprod Biol. 2001 May;96(1):88-97. doi: 10.1016/s0301-2115(00)00382-1.
3
Prostasomes: current concepts.前列腺小体：当前概念
Prostate. 2000 May 15;43(3):169-74. doi: 10.1002/(sici)1097-0045(20000515)43:3<169::aid-pros2>3.0.co;2-d.
4
Prolongation and improvement of prostasome promotive effect on sperm forward motility.延长并增强前列腺小体对精子前向运动的促进作用。
Eur J Obstet Gynecol Reprod Biol. 1995 Feb;58(2):191-8. doi: 10.1016/0028-2243(94)01997-5.
5
Prostasome to sperm transfer of CD13/aminopeptidase N (EC 3.4.11.2).前列腺小体向精子转移CD13/氨肽酶N（EC 3.4.11.2）。
Biochim Biophys Acta. 1997 Oct 20;1336(3):533-8. doi: 10.1016/s0304-4165(97)00071-8.
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Promotive effect by prostasomes on normal human spermatozoa exhibiting no forward motility due to buffer washings.前列腺小体对因缓冲液洗涤而无向前运动能力的正常人精子的促进作用。
Eur J Obstet Gynecol Reprod Biol. 1994 Dec;57(3):181-8. doi: 10.1016/0028-2243(94)90298-4.
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Immunosuppression by human seminal plasma--extracellular organelles (prostasomes) modulate activity of phagocytic cells.
Am J Reprod Immunol. 1992 Sep;28(2):97-103. doi: 10.1111/j.1600-0897.1992.tb00767.x.
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Fusion of sperm with prostasomes: effects on membrane fluidity.精子与前列腺小体的融合：对膜流动性的影响。
Arch Biochem Biophys. 1997 Jul 1;343(1):6-12. doi: 10.1006/abbi.1997.9999.
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Characteristics of human prostasomes isolated from three different sources.从三种不同来源分离出的人前列腺小体的特征。
Prostate. 2003 Mar 1;54(4):322-30. doi: 10.1002/pros.10189.
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Prostasomes: extracellular vesicles from the prostate.前列腺小体：前列腺细胞外囊泡。
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本文引用的文献

1
Occurrence of prostasome-like membrane vesicles in equine seminal plasma.
J Reprod Fertil. 1998 Nov;114(2):237-43. doi: 10.1530/jrf.0.1140237.
2
Identification of dipeptidyl peptidase IV as the antigen of a monoclonal anti-prostasome antibody.鉴定二肽基肽酶IV为一种抗前列腺小体单克隆抗体的抗原。
Prostate. 1999 Jan 1;38(1):35-9. doi: 10.1002/(sici)1097-0045(19990101)38:1<35::aid-pros4>3.0.co;2-j.
3
Antioxidant capacity of prostasomes in human semen.人精液中前列腺小体的抗氧化能力
Mol Hum Reprod. 1998 Jul;4(7):667-72. doi: 10.1093/molehr/4.7.667.
4
Prostasome-like particles in stallion semen.种马精液中的类前列腺小体颗粒。
Biol Reprod. 1998 Aug;59(2):309-13. doi: 10.1095/biolreprod59.2.309.
5
Monoclonal antibodies against human prostasomes.抗人前列腺小体单克隆抗体。
Prostate. 1998 May 15;35(3):178-84. doi: 10.1002/(sici)1097-0045(19980515)35:3<178::aid-pros3>3.0.co;2-d.
6
Motility stimulant effects of prostasome inclusion in swim-up medium on cryopreserved human spermatozoa.
Arch Androl. 1997 May-Jun;38(3):215-21. doi: 10.3109/01485019708994880.
7
Adenosine deaminase binding to human CD26 is inhibited by HIV-1 envelope glycoprotein gp120 and viral particles.HIV-1包膜糖蛋白gp120和病毒颗粒可抑制腺苷脱氨酶与人类CD26的结合。
J Immunol. 1997 Apr 15;158(8):3721-9.
8
Immunohistochemistry of prostasomes from human semen.
Prostate. 1997 Feb 1;30(2):98-106. doi: 10.1002/(sici)1097-0045(19970201)30:2<98::aid-pros5>3.0.co;2-g.
9
Potent blood coagulant activity of human semen due to prostasome-bound tissue factor.
Biol Reprod. 1997 Mar;56(3):757-63. doi: 10.1095/biolreprod56.3.757.
10
Lipid composition in epithelium and stroma of human benign prostatic hyperplasia.人类良性前列腺增生上皮和基质中的脂质成分。
Prostate. 1997 Jan 1;30(1):41-6. doi: 10.1002/(sici)1097-0045(19970101)30:1<41::aid-pros6>3.0.co;2-o.

前列腺小体是人类精液中具有多能性且结构良好的细胞器。

Prostasomes are Pluripotent and Well-Organized Organelles in Human Semen.

作者信息

Gunnar Ronquist

出版信息

EJIFCC. 1999 May 29;11(1):1-5. eCollection 1999 May.

PMID:30720251
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6357244/
Abstract

Prostasomes are submicron, membrane-surrounded organelles produced by the epithelial cells of the human prostate gland and are present in appreciable amounts in normal human semen. The prostasomes are ascribed many functional effects. They have an immunosuppressive capacity by inhibiting the lymphoproliferation and the phagocytosis of macrophages. The prostasomes also regulate the complement activation. They possess an antioxidant capacity. The prostasomes are also able to attach onto washed, prostasome-free spermatozoa and promote the forward motility of the sperm cells.

摘要

前列腺小体是由人类前列腺上皮细胞产生的亚微米级、被膜包围的细胞器，在正常人类精液中含量可观。前列腺小体具有多种功能作用。它们通过抑制淋巴细胞增殖和巨噬细胞的吞噬作用而具有免疫抑制能力。前列腺小体还能调节补体激活。它们具有抗氧化能力。前列腺小体还能够附着在经过洗涤且不含前列腺小体的精子上，并促进精子细胞的向前运动。