Obstetrics Department, Cliniques Universitaires Saint Luc, Brussels, Belgium.
J Matern Fetal Neonatal Med. 2020 Nov;33(21):3579-3583. doi: 10.1080/14767058.2019.1579192. Epub 2019 Feb 22.
The diagnosis of cervical insufficiency is based on the previous history of recurrent second or early third trimester losses. Its incidence among pregnant women is 0.5-1% but can be as high as 75% among women with preterm birth. Transvaginal cerclage (TVC) is the common therapy of cervical insufficiency. However, this technique has several limits, especially in twin pregnancies. As some selected conditions, a transabdominal cerclage (TAC) is indicated, it has been offered to patients with multiple pregnancies. To evaluate the outcomes of twin pregnancies with transabdominal cerclage in terms of preterm birth rate and neonatal morbidity and mortality. We conducted a retrospective study of seven patients with twin pregnancies managed with transabdominal cerclage at the end of the first trimester (12-15 weeks). We selected patients with a history of fetal loss who met the indications criteria of TAC (history of TVC failure or short cervix unable to have TVC). The antenatal and delivery data were collected and compared to those of their previous pregnancy. All patients carried their pregnancy throughout the second trimester and delivered during the third trimester. Mean gestational age was 34 4/7 week. All newborns were alive and neonatal morbidity rate was 50%, mostly related to preterm birth. Mean duration of neonatal intensive care stay was 32 days. There were no operative complications following TAC. Perinatal outcomes are considerably improved in twin pregnancies with transabdominal cerclage. Our findings corroborate those of previous case reports and support the efficacy of TAC for managing cervical insufficiency in twin pregnancies.
宫颈机能不全的诊断基于反复发生的妊娠中期(2 或 3 个月)流产史。其在孕妇中的发病率为 0.5-1%,但在早产孕妇中可高达 75%。经阴道宫颈环扎术(TVC)是宫颈机能不全的常用治疗方法。然而,该技术存在一些局限性,尤其是在双胎妊娠中。在某些选定的情况下,需要进行经腹宫颈环扎术(TAC),它已被提供给多胎妊娠的患者。评估经腹宫颈环扎术治疗双胎妊娠的早产率和新生儿发病率和死亡率。我们对在孕早期(12-15 周)进行经腹宫颈环扎术的 7 例双胎妊娠患者进行了回顾性研究。我们选择了有胎儿丢失史且符合 TAC 适应证标准的患者(TVC 失败史或短宫颈无法进行 TVC)。收集了产前和分娩数据,并与前一次妊娠的数据进行了比较。所有患者均在孕中期分娩,并在孕晚期分娩。平均孕龄为 34 4/7 周。所有新生儿均存活,新生儿发病率为 50%,主要与早产有关。新生儿重症监护病房平均住院时间为 32 天。TAC 后无手术并发症。经腹宫颈环扎术可显著改善双胎妊娠的围产期结局。我们的发现与之前的病例报告一致,并支持 TAC 治疗双胎妊娠宫颈机能不全的疗效。