Nishad A A Nilanga, Arulmoly K, Priyankara S A S, Abeysundara P K
Teaching Hospital, Batticaloa, Sri Lanka.
North Colombo Teaching Hospital, Ragama, Sri Lanka.
Case Reports Immunol. 2019 Jan 2;2019:1676391. doi: 10.1155/2019/1676391. eCollection 2019.
Angiotensin converting enzyme inhibitors (ACEi) are the most commonly used antihypertensives. Therefore, ACEI induced angioedema (ACEi-AE) is not uncommon. Physicians tend to miss the diagnosis whenever a patient is taking the drug for years due to misbelief of "a drug that was taken for years may not be the cause for an allergic reaction or an angioedema". But ACEi can induce angioedema after many years of usage as well as sometimes after stopping the drug even. Most of the emergency physicians and centers are not aware of clinical diagnosis and diagnostic criteria including available diagnostic tests and more importantly the treatment options of ACEi-AE. Therefore not only the diagnosis is delayed or missing but also proper treatment options are not practiced at many emergency rooms and at wards.
血管紧张素转换酶抑制剂（ACEi）是最常用的抗高血压药物。因此，ACEi诱发的血管性水肿（ACEi-AE）并不罕见。由于存在“服用多年的药物可能不是过敏反应或血管性水肿的原因”这种错误观念，每当患者服用该药物多年时，医生往往会漏诊。但ACEi在使用多年后以及有时甚至在停药后都可能诱发血管性水肿。大多数急诊医生和急救中心并不了解ACEi-AE的临床诊断和诊断标准，包括可用的诊断测试，更重要的是其治疗选择。因此，不仅诊断会延迟或漏诊，而且许多急诊室和病房也没有采用适当的治疗方案。
