Gilbert Donald G
Indiana University, Bloomington, IN, USA.
PeerJ. 2019 Feb 1;7:e6374. doi: 10.7717/peerj.6374. eCollection 2019.
The pig is a well-studied model animal of biomedical and agricultural importance. Genes of this species, , are known from experiments and predictions, and collected at the NCBI reference sequence database section. Gene reconstruction from transcribed gene evidence of RNA-seq now can accurately and completely reproduce the biological gene sets of animals and plants. Such a gene set for the pig is reported here, including human orthologs missing from current NCBI and Ensembl reference pig gene sets, additional alternate transcripts, and other improvements. Methodology for accurate and complete gene set reconstruction from RNA is used: the automated SRA2Genes pipeline of EvidentialGene project.
猪是一种在生物医学和农业领域具有重要研究价值的模式动物。通过实验和预测，人们已经了解了该物种的基因，并将其收集在NCBI参考序列数据库部分。现在，基于RNA-seq转录基因证据的基因重建能够准确、完整地再现动植物的生物学基因集。本文报道了这样一个猪的基因集，包括当前NCBI和Ensembl参考猪基因集中缺失的人类直系同源基因、额外的可变转录本以及其他改进。我们采用了从RNA准确、完整重建基因集的方法：EvidentialGene项目的自动化SRA2Genes流程。
