一例由拉科酰胺引起的听觉障碍病例。

Kawai Mihoko, Kanemoto Kousuke

Department of Neuropsychiatry, Aichi Medical University, 1-1, Karimata, Yazako, Nagakute-shi, Aichi 480-1195, Japan.

Epilepsy Behav Case Rep. 2019 Jan 12;11:70-72. doi: 10.1016/j.ebcr.2018.12.001. eCollection 2019.

We report a case of auditory disturbance in an adult female that developed after starting lacosamide treatment for epilepsy. While carbamazepine is known to change auditory pitch perception in some patients, that has not been previously reported as a side effect of lacosamide administration. In our description of pitch perception deficit associated with lacosamide, we outline features seen in our patient and compare our findings with those of previous reports describing carbamazepine-associated auditory disturbance.

我们报告了一例成年女性在开始使用拉科酰胺治疗癫痫后出现听觉障碍的病例。虽然已知卡马西平会改变一些患者的听觉音调感知，但此前尚未有拉科酰胺给药导致这种情况的副作用报道。在我们对与拉科酰胺相关的音调感知缺陷的描述中，我们概述了在我们患者身上观察到的特征，并将我们的发现与之前描述卡马西平相关听觉障碍的报告结果进行比较。