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心血管代谢疾病

Cardiometabolic diseases.

作者信息

Ferreira Sandra Roberta Gouvea, Chiavegatto Filho Alexandre Dias Porto, Lebrão Maria Lúcia, Duarte Yeda Aparecida de Oliveira, Laurenti Ruy

机构信息

Departamento de Epidemiologia, Faculdade de Saúde Pública, Universidade de São Paulo - São Paulo (SP), Brasil.

Departamento de Enfermagem Médico-Cirúrgica, Escola de Enfermagem, Universidade de São Paulo - São Paulo (SP), Brasil.

出版信息

Rev Bras Epidemiol. 2019 Feb 4;21Suppl 02(Suppl 02):e180008. doi: 10.1590/1980-549720180008.supl.2.

Abstract

INTRODUCTION

Cardiometabolic diseases are prevalent in populations and are among the leading causes of death. Objective: This sub-study of the Health, Well-being and Aging (SABE) study describes the self-reported prevalence of diabetes mellitus (DM), hypertension, and atherosclerotic cardiovascular disease (CVD) for its three waves (2000, 2006, and 2010). It also analyses the associations with selected risk factors.

METHODS

Logistic regression models were performed.

RESULTS

Predominance of women and average age (68 years) were maintained in all the waves. During the period, there was a general tendency of increasing prevalence of hypertension (53.1 to 66.7%), DM (16.7 to 25.0%), and CVD (23.0 to 27.2%); and stabilization of the CVD prevalence rate occurred only from 2006 to 2010. Women, with body mass index (BMI) > 27 kg/m2, and ex-smokers had consistently higher risk of self-reported hypertension across the three waves. BMI >27kg/m2 was also associated with a higher probability of DM in the three waves, whereas with ex-smokers this occurred only in 2010. Ex-smokers presented higher risk of CVD in all the waves, but not excess weight. Wave pairs were analyzed to test changes in prevalence, and it was found a significant increase in diseases rates across the years.

CONCLUSION

In summary, self-reported DM, hypertension, and CVD had high prevalence rates for participants of SABE Study, in São Paulo. The association of elevated BMI with cardiometabolic diseases suggests that body adiposity might favor their occurrence, although the study design does not guarantee a cause and effect relationship. Increased rates of affected individuals from the first to the third wave may reflect improvement in diagnostic conditions and/or control of these diseases' mortality during that period.

摘要

引言

心脏代谢疾病在人群中普遍存在,是主要死因之一。目的:本健康、幸福与衰老(SABE)研究的子研究描述了其三个时间点(2000年、2006年和2010年)自我报告的糖尿病(DM)、高血压和动脉粥样硬化性心血管疾病(CVD)患病率。它还分析了与选定风险因素的关联。

方法

进行逻辑回归模型分析。

结果

在所有时间点,女性占主导且平均年龄为68岁。在此期间,高血压(从53.1%升至66.7%)、糖尿病(从16.7%升至25.0%)和心血管疾病(从23.0%升至27.2%)的患病率总体呈上升趋势;仅在2006年至2010年期间心血管疾病患病率趋于稳定。在三个时间点,体重指数(BMI)>27kg/m²的女性和曾经吸烟者自我报告患高血压的风险一直较高。BMI>27kg/m²在三个时间点也与患糖尿病的较高概率相关,而曾经吸烟者仅在2010年出现这种情况。在所有时间点,曾经吸烟者患心血管疾病的风险较高,但超重者并非如此。分析各时间点配对数据以测试患病率变化,发现这些疾病的发病率多年来显著增加。

结论

总之,对于圣保罗SABE研究的参与者,自我报告的糖尿病、高血压和心血管疾病患病率很高。BMI升高与心脏代谢疾病的关联表明身体肥胖可能有利于这些疾病的发生,尽管研究设计不能保证因果关系。从第一波到第三波受影响个体的增加可能反映了该时期诊断条件的改善和/或这些疾病死亡率的控制情况。

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