Arnold & Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY, USA.
Department of Pharmacy, The Brooklyn Hospital Center, Long Island University, Brooklyn, NY, USA.
J Pharm Pract. 2020 Jun;33(3):364-367. doi: 10.1177/0897190019825965. Epub 2019 Feb 6.
To report a case of sudden cardiac arrest possibly associated with the administration of GoLytely (polyethylene glycol 3350 and electrolytes).
A 60-year-old male with a history of hypertension, hyperlipidemia, type 2 diabetes, and coronary artery disease presented to the emergency department with complaints of constipation and lower abdominal pain over the past week, and the inability to urinate over the past day. The patient had received GoLytely as treatment to alleviate symptoms of constipation and abdominal pain. However, several hours after administration of the bowel prep solution, the patient suffered an episode of cardiac arrest. After ruling out other possible etiologies, GoLytely was suspected as a possible cause of cardiac arrest. The patient had suffered an anoxic brain injury and remained intubated and unconscious until he eventually expired, 20 days after the event.
Although GoLytely appears to be a safe agent with fewer side effects, clinicians need to be mindful of potential life-threatening adverse events following GoLytely administration and monitor patients closely during and after administration.
报告 1 例可能与给予聚乙二醇电解质散（聚乙二醇 3350 和电解质）相关的心脏骤停病例。
一名 60 岁男性，有高血压、高血脂、2 型糖尿病和冠心病病史，因过去一周出现便秘和下腹痛、过去一天无法排尿来就诊。患者接受聚乙二醇电解质散治疗以缓解便秘和腹痛症状。然而，在给予肠道准备溶液数小时后，患者发生了心脏骤停。在排除其他可能的病因后，怀疑聚乙二醇电解质散是心脏骤停的可能原因。患者发生了缺氧性脑损伤，一直插管且无意识，最终在事件发生 20 天后死亡。
尽管聚乙二醇电解质散似乎是一种安全的药物，副作用较少，但临床医生需要注意在给予聚乙二醇电解质散后可能发生危及生命的不良事件，并在给予药物期间和之后密切监测患者。
