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阈值会影响龋病风险评估的预测准确性。

Threshold values affect predictive accuracy of caries risk assessment.

机构信息

a Department of Oral and Maxillofacial Radiology, Faculty of Odontology , Malmö University , Malmö , Sweden.

b Department of Oral Biology, Faculty of Odontology , Malmö University , Malmö , Sweden.

出版信息

Acta Odontol Scand. 2019 May;77(4):315-327. doi: 10.1080/00016357.2018.1564838. Epub 2019 Feb 6.

Abstract

OBJECTIVE

To evaluate effects of thresholds on estimates of predictive accuracy of methods for caries risk assessment.

MATERIAL AND METHODS

Adolescents, aged 12 visiting two dental clinics, were examined by visual/tactile examination and bitewing radiography at baseline and after one year. Three methods for caries risk assessment were applied: previous caries experience, dentists' risk assessment according to set criteria (presence or absence of caries lesion) and acid tolerance of dental biofilm. The measure for validity (the reference standard) comprised caries lesion progression at 1 year. Predictive accuracy estimates were calculated for several thresholds.

RESULTS

Accuracy estimates changed with threshold values of the methods and the reference standard. Patient spectrum differed between the clinics, which resulted in different accuracy estimates for the two samples. Generally, negative predictive values were high while positive ones were low indicating that these methods were more efficient in finding individuals who are at low risk of developing caries lesions than those with increased risk.

CONCLUSIONS

As thresholds and patient spectrum affected predictive accuracy, it may be difficult to design a universal model with set thresholds for caries risk assessment. Foremost, a model should consider the level of aspiration for prediction and clinical decisions that will be made based on the risk assessment in the actual clinical setting.

摘要

目的

评估阈值对龋病风险评估方法预测准确性估计的影响。

材料和方法

对 12 岁的青少年在基线和一年后分别进行视诊/触诊检查和牙合翼片检查。应用三种龋病风险评估方法:既往龋病史、牙医根据设定标准(有无龋病病变)进行的风险评估和牙菌斑耐酸性。有效性的衡量标准(参考标准)包括 1 年内龋病病变进展。为几个阈值计算了预测准确性估计。

结果

准确性估计随方法和参考标准的阈值值而变化。诊所之间的患者谱不同,导致两个样本的准确性估计不同。一般来说,阴性预测值较高,阳性预测值较低,表明这些方法在发现低龋病风险个体方面更有效,而在发现高风险个体方面效率较低。

结论

由于阈值和患者谱会影响预测准确性,因此为龋病风险评估设计具有设定阈值的通用模型可能具有挑战性。最重要的是,模型应考虑预测的期望水平以及根据实际临床环境中风险评估做出的临床决策。

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