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间歇性跛行患者的治疗策略

Treatment Strategies for the Claudicant.

作者信息

Pereira Keith

机构信息

Division of Vascular and Interventional Radiology, Saint Louis University, St. Louis, Missouri.

出版信息

Semin Intervent Radiol. 2018 Dec;35(5):435-442. doi: 10.1055/s-0038-1676322. Epub 2019 Feb 5.

Abstract

Peripheral arterial disease (PAD) is a prevalent, morbid, and mortal disease. Claudication represents an early, yet common manifestation of PAD. A clinical history and physical examination combined with an ankle-brachial index can help make a diagnosis of claudication. Due to the polyvascular nature of the underlying atherosclerosis, PAD is often associated with heart disease and stroke. Although health implications of PAD derive from both its limb and cardiovascular manifestations, claudication is life-threatening, less limb-threatening. Medical modification of cardiovascular risk factors and exercise are the cornerstone in the treatment of claudication. Revascularization in claudication is focused at improvement in claudication symptoms and functional status, rather than aggressive attempts at limb salvage. The aim of this article is to summarize the strategies in the treatment of claudication, to serve as a concise and informative reference for physicians who are managing these patients. A framework of the decision-making process in the management of patients with claudication is shown, which can be applied in clinical practice.

摘要

外周动脉疾病(PAD)是一种常见、致残且致命的疾病。间歇性跛行是PAD的一种早期但常见的表现。临床病史、体格检查以及踝肱指数有助于诊断间歇性跛行。由于潜在动脉粥样硬化具有多血管性,PAD常与心脏病和中风相关。尽管PAD对健康的影响源于其肢体和心血管表现,但间歇性跛行虽危及生命,但对肢体威胁较小。对心血管危险因素进行医学干预和运动是治疗间歇性跛行的基石。间歇性跛行的血运重建主要旨在改善间歇性跛行症状和功能状态,而非积极尝试挽救肢体。本文旨在总结间歇性跛行的治疗策略,为管理这些患者的医生提供一份简洁且信息丰富的参考资料。文中展示了一个管理间歇性跛行患者的决策过程框架,可应用于临床实践。

相似文献

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Treatment Strategies for the Claudicant.间歇性跛行患者的治疗策略
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Treatment of chronic peripheral arterial disease.慢性外周动脉疾病的治疗。
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本文引用的文献

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Medical Management of Functional Impairment in Peripheral Artery Disease: A Review.外周动脉疾病功能障碍的医学管理:综述。
Prog Cardiovasc Dis. 2018 Mar-Apr;60(6):586-592. doi: 10.1016/j.pcad.2018.03.007. Epub 2018 May 1.
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Graft type for femoro-popliteal bypass surgery.股腘动脉搭桥手术的移植物类型。
Cochrane Database Syst Rev. 2018 Feb 11;2(2):CD001487. doi: 10.1002/14651858.CD001487.pub3.
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Exercise for intermittent claudication.间歇性跛行的运动疗法
Cochrane Database Syst Rev. 2017 Dec 26;12(12):CD000990. doi: 10.1002/14651858.CD000990.pub4.
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Medical management of claudication.间歇性跛行的医学管理。
J Vasc Surg. 2017 Jul;66(1):275-280. doi: 10.1016/j.jvs.2017.02.040. Epub 2017 May 19.
9
Peripheral artery disease: epidemiology and global perspectives.外周动脉疾病:流行病学和全球视角。
Nat Rev Cardiol. 2017 Mar;14(3):156-170. doi: 10.1038/nrcardio.2016.179. Epub 2016 Nov 17.

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