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多西他赛诱导的转移性前列腺腺癌患者发生史蒂文斯-约翰逊综合征

Docetaxel-Induced Stevens-Johnson Syndrome in a Patient with Metastatic Prostate Adenocarcinoma.

作者信息

Diab Osama, Mcentire Dan, Kassim Thamer, Nayfeh Ali, Dajani Abdel Rahman, Kerfeld Mitchell, Campbell Jonathon, Alsuwaidan Adbullah, Hazeem Mahmoud Abu, Gbadamosi-Akindele Maryam

机构信息

Department of Medicine, Creighton University, Omaha, NE, USA.

Department of Medicine, University of Utah, Salt Lake City, UT, USA.

出版信息

Case Rep Oncol Med. 2019 Jan 8;2019:7928752. doi: 10.1155/2019/7928752. eCollection 2019.

DOI:10.1155/2019/7928752
PMID:30729055
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6341237/
Abstract

Docetaxel is a commonly used chemotherapeutic agent in a variety of cancer treatment regimens. We present a case of apparent docetaxel-induced Stevens-Johnson syndrome (SJS) in a patient recently treated for metastatic prostate cancer. This medication is not classically associated with the development of SJS but in our case, along with a number of other case reports, and a single phase II clinical trial, an association was recognized. We encourage clinicians who employ the use of this medication to be aware of this relationship.

摘要

多西他赛是多种癌症治疗方案中常用的化疗药物。我们报告了1例近期接受转移性前列腺癌治疗的患者出现明显的多西他赛诱导的史蒂文斯-约翰逊综合征(SJS)的病例。这种药物通常与SJS的发生无关联,但在我们的病例中,连同其他一些病例报告以及一项II期临床试验,发现了这种关联。我们鼓励使用这种药物的临床医生注意这种关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cb8/6341237/12a8d784c667/CRIONM2019-7928752.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cb8/6341237/7f599880b176/CRIONM2019-7928752.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cb8/6341237/12a8d784c667/CRIONM2019-7928752.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cb8/6341237/7f599880b176/CRIONM2019-7928752.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cb8/6341237/12a8d784c667/CRIONM2019-7928752.002.jpg

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Adv Ther. 2017 Jun;34(6):1235-1244. doi: 10.1007/s12325-017-0530-y. Epub 2017 Apr 24.
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The Epidemiology of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in the UK.英国史蒂文斯-约翰逊综合征和中毒性表皮坏死松解症的流行病学
J Invest Dermatol. 2017 Jun;137(6):1240-1247. doi: 10.1016/j.jid.2017.01.031. Epub 2017 Feb 12.
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Toxicities of docetaxel: original drug versus generics-a comparative study about 81 cases.
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