Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Department of Geriatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Aging Ment Health. 2020 Jun;24(6):889-897. doi: 10.1080/13607863.2019.1571012. Epub 2019 Feb 7.
To examine the association of social network size and loneliness with cognitive performance and -decline in depressed older adults. A sample of 378 older adults [70.7 (7.4) years] with a diagnosis of current depressive disorder were recruited from primary care and specialized mental health care. Cognitive performance was assessed at baseline and 2 years follow-up with the Stroop colored-word test, a modified version of the Auditory Verbal Learning Task and the Digit Span subtest from the Wechsler Adult Intelligence Scale, encompassing four cognitive domains; processing speed, interference control, memory, and working memory. Social network size was assessed with the Close Person Inventory and loneliness with the de Jong Gierveld Loneliness Scale at baseline. After adjusting for baseline working memory performance, loneliness was associated with impaired working memory after 2 years [B = -0.08 (-0.17 to 0.00)]. This association was no longer significant after adjusting for age, sex, education level, physical activity, alcohol use and depressive symptom severity [B = -0.07 (-0.16 to 0.03)]. A backward elimination procedure revealed education level to be the only covariable to explain this association. Loneliness was not associated with impairments or decline in other cognitive domains. Social network size was not associated with cognitive impairments or decline. Social network size and loneliness do not predict cognitive decline in depressed older adults.
探讨社交网络规模和孤独感与抑郁老年患者认知表现和认知衰退的相关性。方法：本研究纳入了 378 名年龄在 70.7（7.4）岁的、当前被诊断为抑郁障碍的老年患者，他们来自初级保健和专门的精神卫生保健机构。在基线和 2 年随访时，使用 Stroop 彩色单词测试、听觉词语学习任务的改良版以及韦氏成人智力量表的数字跨度子测验评估认知表现，这些测试涵盖了四个认知领域：加工速度、干扰控制、记忆和工作记忆。在基线时，使用亲密关系量表评估社交网络规模，使用 Jong-Gierveld 孤独量表评估孤独感。在调整基线工作记忆表现后，孤独感与 2 年后的工作记忆障碍相关（B = -0.08 [-0.17 至 0.00]）。在调整年龄、性别、教育程度、身体活动、饮酒和抑郁症状严重程度后，这种相关性不再显著（B = -0.07 [-0.16 至 0.03]）。向后消除程序显示，教育程度是解释这种相关性的唯一协变量。孤独感与其他认知领域的损伤或衰退无关。社交网络规模与认知损伤或衰退无关。社交网络规模和孤独感不能预测抑郁老年患者的认知衰退。
