Scientific and Technological Area, Department of Neurology, Italian National Research Center On Aging (IRCCS INRCA), 60124 Ancona, Italy.
Department of Mental Health, ASP Basilicata, 85100 Potenza, Italy.
Int J Environ Res Public Health. 2023 Feb 1;20(3):2615. doi: 10.3390/ijerph20032615.
Multimorbidity has been associated with adverse health outcomes, such as reduced physical function, poor quality-of-life (QoL), poor self-rated health.
The association between quality of life, social support, sense of loneliness and sex and age in older adult patients affected by two or more chronic diseases (multimorbidity) was evaluated.
Patients n. 162 with multimorbidity and living with family members.
MMSE-Mini-Mental-State-Examination; ADL-Activities of Daily Living; Social Schedule: demographic variables; Loneliness Scale -de Jong Gierveld; Quality-of-Life-FACT-G; WHOQOL-BRIEF Social relationships.
Multivariate Regression Analysis.
The patients with three or more diseases have worse dimensions of FACT-G total score ( = 0.029), QoL Physical-well-being ( = 0.003), Social well-being ( = 0.003), Emotional-well-being ( = 0.012), Functional-well-being ( < 0.001), than those with two. Multiple linear regression QoL: FACT_G total score, PWB, SWB, EWB, FWB as dependent variables. In the presence of multimorbidity with an increase in the patient's age FACT-G total score (B = -0.004, = 0.482), PWB (B = -0.024, = 0.014), SWB (B = -0.022, = 0.051), EWB (B = -0.001, = 0.939), FWB (B = -0.023, = 0.013) decrease by an average of 0.1, and as the sense of solitude increases FACT-G total score (B = -0.285, < 0.000), PWB (B = -0.435, < 0.000), SWB(B = -0.401, < 0.000), EWB(B = -0.494, < 0.000), FWB(B = -0.429, < 0.000) decrease by 0.4.
A sense of loneliness and advancing age are associated with bad quality-of life in self-sufficient elderly patients with multimorbidity.
Demonstrating that loneliness, as well as in the presence of interpersonal relations, is predictive of worse quality of life in patients with multimorbidity helps identify people most at risk for common symptoms and lays the groundwork for research concerning both diagnosis and treatment.
多种疾病与不良健康结果相关，例如身体功能下降、生活质量（QoL）差、自我健康评价差。
评估患有两种或两种以上慢性疾病（多种疾病）的老年患者的生活质量、社会支持、孤独感和性别与年龄之间的关系。
纳入 162 名患有多种疾病且与家庭成员一起生活的患者。
MMSE-Mini-Mental-State-Examination；ADL-Activities of Daily Living；Social Schedule：人口统计学变量；孤独感量表 -de Jong Gierveld；生活质量 FACT-G；WHOQOL-BRIEF 社会关系。
多变量回归分析。
患有三种或更多疾病的患者在 FACT-G 总分（ = 0.029）、生活质量身体状况（ = 0.003）、社会关系（ = 0.003）、情感状况（ = 0.012）、功能状况（ < 0.001）方面的维度较差，而患有两种疾病的患者则较差。多元线性回归生活质量：FACT_G 总分、PWB、SWB、EWB、FWB 作为因变量。在患有多种疾病且患者年龄增加的情况下，FACT-G 总分（B = -0.004， = 0.482）、PWB（B = -0.024， = 0.014）、SWB（B = -0.022， = 0.051）、EWB（B = -0.001， = 0.939）、FWB（B = -0.023， = 0.013）平均下降 0.1，孤独感增加时，FACT-G 总分（B = -0.285， < 0.000）、PWB（B = -0.435， < 0.000）、SWB（B = -0.401， < 0.000）、EWB（B = -0.494， < 0.000）、FWB（B = -0.429， < 0.000）平均下降 0.4。
孤独感和年龄增长与患有多种疾病的自理老年患者的生活质量较差有关。
证明孤独感以及人际关系的存在与多种疾病患者的生活质量较差有关，这有助于确定最容易出现常见症状的人群，并为有关诊断和治疗的研究奠定基础。
