• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

提高对神经精神并发症的认识、检测和管理:是优化帕金森病治疗的必要组成部分。

Improved understanding, detection, and management of neuropsychiatric complications: essential components to the optimal treatment of Parkinson's disease.

机构信息

Rutgers,The State University of New Jersey,Robert Wood Johnson Medical School,Piscataway,NJ,USA.

出版信息

Int Psychogeriatr. 2019 Jan;31(1):1-4. doi: 10.1017/S1041610219000048.

DOI:10.1017/S1041610219000048
PMID:30729909
Abstract

It has been well established that Parkinson's disease (PD) is not just a movement disorder (Weintraub and Burn, 2011). Fortunately, the past two decades have seen increased attention to the neuropsychiatric aspects of the disease process. Neuropsychiatric symptoms (e.g., mood, sleep, psychosis, and impulse control) are experienced by the overwhelming majority of people living with PD (PWP) and have a detrimental impact on physical and cognitive decline (Pontone et al., 2016), quality of life (van Uem et al., 2016), and caregiving relationships (Santos-García, 2015). As a field, all multidisciplinary providers involved in the care of PWP, inclusive of movement disorder specialists, geriatric psychiatrists, clinical psychologists, social workers, and other allied healthcare providers, must work to improve the recognition and treatment of key non-motor symptoms, such as depression and anxiety, as part of the standard of care (Cohen et al., 2016). Improved detection and management is critical, as the failure to appropriately treat psychiatric complications negatively impacts the overall course of the illness, functional aspects of daily life, and the PWP ability to fully engage in their own self-care (Pontone et al., 2016).

摘要

帕金森病(PD)不仅仅是一种运动障碍,这一点已经得到充分证实(Weintraub 和 Burn,2011)。幸运的是,在过去的二十年中,人们越来越关注疾病过程中的神经精神方面。神经精神症状(例如情绪、睡眠、精神病和冲动控制障碍)是绝大多数帕金森病患者(PWP)所经历的,对身体和认知能力下降(Pontone 等人,2016)、生活质量(van Uem 等人,2016)和照护关系(Santos-García,2015)都有不利影响。作为一个领域,所有参与 PWP 护理的多学科提供者,包括运动障碍专家、老年精神病学家、临床心理学家、社会工作者和其他相关医疗保健提供者,都必须努力提高对关键非运动症状(如抑郁和焦虑)的识别和治疗水平,这是护理标准的一部分(Cohen 等人,2016)。提高检测和管理水平至关重要,因为未能适当治疗精神并发症会对疾病的整体进程、日常生活的功能方面以及 PWP 充分参与自身自我护理的能力产生负面影响(Pontone 等人,2016)。

相似文献

1
Improved understanding, detection, and management of neuropsychiatric complications: essential components to the optimal treatment of Parkinson's disease.提高对神经精神并发症的认识、检测和管理:是优化帕金森病治疗的必要组成部分。
Int Psychogeriatr. 2019 Jan;31(1):1-4. doi: 10.1017/S1041610219000048.
2
Psychiatric predictors of quality of life in Parkinson's disease: A three-year longitudinal study.帕金森病患者生活质量的精神预测因素:一项为期三年的纵向研究。
J Neurol Sci. 2024 Nov 15;466:123248. doi: 10.1016/j.jns.2024.123248. Epub 2024 Sep 18.
3
[Neuropsychiatric manifestations in Parkinson's disease].[帕金森病的神经精神表现]
Psychiatriki. 2015 Apr-Jun;26(2):116-30.
4
A general clinical overview of the non-motor symptoms in Parkinson's disease: Neuropsychiatric symptoms.帕金森病非运动症状的一般临床概述:神经精神症状
Int Rev Neurobiol. 2024;174:59-97. doi: 10.1016/bs.irn.2023.11.001. Epub 2024 Jan 15.
5
Prediction of depression and anxiety via patient-assessed tremor severity, not physician-reported motor symptom severity, in patients with Parkinson's disease or essential tremor who have undergone deep brain stimulation.通过接受深部脑刺激的帕金森病或特发性震颤患者自我评估的震颤严重程度而非医生报告的运动症状严重程度来预测抑郁和焦虑。
J Neurosurg. 2018 Dec 1;129(6):1562-1571. doi: 10.3171/2017.8.JNS1733. Epub 2018 Feb 23.
6
Cognitive performance and neuropsychiatric symptoms in early, untreated Parkinson's disease.早期未经治疗的帕金森病患者的认知功能和神经精神症状
Mov Disord. 2015 Jun;30(7):919-27. doi: 10.1002/mds.26170. Epub 2015 Mar 4.
7
Managing non-motor symptoms of Parkinson disease in China: clinical perspectives.中国帕金森病非运动症状的管理:临床视角
BMC Neurol. 2025 Apr 17;25(1):168. doi: 10.1186/s12883-025-04175-8.
8
Impact of anxiety, apathy and reduced functional autonomy on perceived quality of life in Parkinson's disease.焦虑、冷漠和功能自主性降低对帕金森病患者生活质量的影响。
Parkinsonism Relat Disord. 2017 Oct;43:114-117. doi: 10.1016/j.parkreldis.2017.08.003. Epub 2017 Aug 5.
9
Treatment of Nonmotor Symptoms in Parkinson's Disease.帕金森病非运动症状的治疗
Int Rev Neurobiol. 2017;132:361-379. doi: 10.1016/bs.irn.2017.03.002. Epub 2017 May 3.
10
Neuropsychiatric Complications of Parkinson Disease Treatments: Importance of Multidisciplinary Care.帕金森病治疗的神经精神并发症:多学科护理的重要性。
Am J Geriatr Psychiatry. 2016 Dec;24(12):1171-1180. doi: 10.1016/j.jagp.2016.08.017. Epub 2016 Sep 3.

引用本文的文献

1
Characterization of substantia nigra neurogenesis in homeostasis and dopaminergic degeneration: beneficial effects of the microneurotrophin BNN-20.黑质神经发生的特征:在自稳态和多巴胺能变性中的作用:微量神经生长因子 BNN-20 的有益作用。
Stem Cell Res Ther. 2021 Jun 10;12(1):335. doi: 10.1186/s13287-021-02398-3.
2
The Relationship Between Anxiety Disorders and Parkinson's Disease: Clinical and Therapeutic Issues.焦虑障碍与帕金森病的关系:临床与治疗问题。
Curr Psychiatry Rep. 2021 Mar 3;23(4):20. doi: 10.1007/s11920-021-01229-9.
3
Clinical Characterization of Parkinson's Disease Patients With Cognitive Impairment.
帕金森病认知障碍患者的临床特征
Front Neurol. 2020 Aug 4;11:731. doi: 10.3389/fneur.2020.00731. eCollection 2020.
4
Regulation of BDNF-TrkB Signaling and Potential Therapeutic Strategies for Parkinson's Disease.脑源性神经营养因子-酪氨酸激酶受体B信号通路的调控及帕金森病的潜在治疗策略
J Clin Med. 2020 Jan 17;9(1):257. doi: 10.3390/jcm9010257.
5
A Qualitative Study on the Impact of First Steps-A Peer-led Educational Intervention for People Newly Diagnosed with Parkinson's Disease.一项关于“第一步”——由同伴主导的针对帕金森病新诊断患者的教育干预影响的定性研究。
Behav Sci (Basel). 2019 Oct 10;9(10):107. doi: 10.3390/bs9100107.