Buckshey Sakshi, Anthonappa Robert P, King Nigel M, Itthagarun Anut
J Clin Pediatr Dent. 2019;43(2):103-108. doi: 10.17796/1053-4625-43.2.6. Epub 2019 Feb 7.
Calcium phosphate and fluoride (F) delivery systems claim to facilitate enamel remineralization.
To evaluate and compare (i) the remineralizing potential of Clinpro Tooth Crème(CTC) and Tooth Mousse Plus(TMP) on artificial carious lesions, and (ii) the benefit of 1000ppm F dentifrice prior to the application of CTC and TMP.
Carious lesions, 200-300μm deep were produced by placing molars in demineralizing solution for 96h, sections 100-150μm thick were then randomly assigned to six groups(n=150). Specimens were treated thrice daily with a non-fluoridated(Group A), or fluoridated dentifrice[1000ppm, (Group B)], or CTC(Group C), TMP(Group D), fluoridated dentifrice followed by CTC(Group E), or a fluoridated dentifrice followed by TMP(Group F), and then subjected to a 10-day pH cycling model. Lesion evaluation involved polarizing light microscopy and microradiography.
Posttreatment maximum mineral content at the surface zone(V) was significantly increased in Groups B, C, and D compared to the other groups. The lesion depth(LD) decreased in Group D>Group C>Group E, and the net mineral content gain(ΔZ) in Group C>Group D, which did not reach statistical significance.
CTC and TMP exhibited similar efficacy in remineralizing artificial carious lesions. Nevertheless, the net mineral gain or lesion consolidation following CTC use was higher than TMP.
磷酸钙和氟化物输送系统宣称有助于牙釉质再矿化。
评估并比较(i)Clinpro Tooth Crème(CTC)和Tooth Mousse Plus(TMP)对人工龋损的再矿化潜力,以及(ii)在使用CTC和TMP之前使用含1000ppm氟牙膏的益处。
通过将磨牙置于脱矿溶液中96小时产生深度为200 - 300μm的龋损,然后将100 - 150μm厚的切片随机分为六组(n = 150)。标本每天用不含氟牙膏(A组)、含氟牙膏[1000ppm,(B组)]、CTC(C组)、TMP(D组)、含氟牙膏后接CTC(E组)或含氟牙膏后接TMP(F组)处理三次,然后进行10天的pH循环模型。病变评估包括偏光显微镜和显微放射摄影。
与其他组相比,B组、C组和D组治疗后表面区域(V)的最大矿物质含量显著增加。病变深度(LD)在D组>C组>E组中降低,C组的净矿物质含量增加(ΔZ)>D组,但未达到统计学显著性。
CTC和TMP在人工龋损再矿化方面表现出相似的功效。然而,使用CTC后的净矿物质增加或病变巩固高于TMP。