Gazel Eymen, Kaya Engin, Yalcin Serdar, Aybal Halil Çagri, Aydogan Tahsin Batuhan, Tunc Lutfi
Department of Urology, Acıbadem University Ankara Hospital, Ankara, Turkey.
Department of Urology, Health Science University Gulhane Training and Research Hospital, Ankara, Turkey,
Urol Int. 2019;102(3):306-310. doi: 10.1159/000496173. Epub 2019 Feb 7.
Holmium laser enucleation of the prostate (HoLEP) is becoming the new standard procedure for treating benign prostatic hyperplasia (BPH), a common condition in aging men. Most studies have focused on proving its efficacy in treating large prostates. In this study, we compared its efficacy in treating small (< 80 mL) and large (> 80 mL) prostates.
This prospective study included 119 patients with BPH who underwent HoLEP by the same surgeon between June 2015 and December 2017. They were divided into 2 groups according to their prostate volumes (≤80 mL: Group 1; > 80 mL: Group 2). Various pre- and postoperative parameters were compared within and between the groups.
International Prostate Symptom Score (IPSS), postvoid residual (PVR) volume, and voiding time (VT) significantly decreased, and the peak urinary flow rate (Qmax), average urinary flow rate (Qave), and quality of life (QoL) score significantly increased postoperatively in both groups. The postoperative changes in IPSS, QoL score, Qmax, Qave, VT, PVR volume, and hemoglobin levels were not significantly different between the groups. In addition, no significant difference was observed in postoperative complications between the groups.
Our results indicate that HoLEP is an effective procedure for treating both small and large prostates.
钬激光前列腺剜除术（HoLEP）正成为治疗良性前列腺增生（BPH）的新标准术式，BPH是老年男性的常见病症。大多数研究都集中在证明其治疗大体积前列腺的疗效。在本研究中，我们比较了其治疗小体积（<80 mL）和大体积（>80 mL）前列腺的疗效。
这项前瞻性研究纳入了2015年6月至2017年12月期间由同一位外科医生为119例BPH患者实施HoLEP手术。根据前列腺体积将他们分为两组（≤80 mL：第1组；>80 mL：第2组）。对组内和组间的各种术前和术后参数进行了比较。
两组患者术后国际前列腺症状评分（IPSS）、残余尿量（PVR）体积和排尿时间（VT）均显著降低，最大尿流率（Qmax）、平均尿流率（Qave）和生活质量（QoL）评分均显著升高。两组患者术后IPSS、QoL评分、Qmax、Qave、VT、PVR体积和血红蛋白水平的变化无显著差异。此外，两组术后并发症无显著差异。
我们的结果表明，HoLEP是治疗小体积和大体积前列腺的有效方法。
