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钬激光前列腺剜除术治疗排尿或储尿期下尿路症状良性前列腺增生患者的疗效比较。一项对照研究。

Is Holmium Laser Enucleation of Prostate equally effective in management of benign prostatic hyperplasia patients with either voiding or storage lower urinary tract symptoms? A comparative study.

机构信息

Division of Urology, Department of Surgery, University of Cincinnati College of Medicine, Cincinnati (US); Asiut University Hospitals, Asiut, Egypt.

Division of Urology, Department of Surgery, University of Cincinnati College of Medicine, Cincinnati.

出版信息

Arch Ital Urol Androl. 2022 Jun 29;94(2):174-179. doi: 10.4081/aiua.2022.2.174.

DOI:10.4081/aiua.2022.2.174
PMID:35775342
Abstract

OBJECTIVE

To evaluate and compare the effectiveness and safety of holmium laser enucleation of prostate (HoLEP) in relieving either voiding or storage lower urinary tract symptoms (LUTS) in benign prostatic hyperplasia (BPH) patients.

MATERIALS AND METHODS

The charts of patients with BPH who underwent HoLEP for either predominant voiding or predominant storage LUTS at University of Cincinnati hospitals in the period between February 2015 and December 2020 were retrospectively reviewed and analyzed for changes in voiding symptomatology, storage symptomatology, hematuria, International Prostate Symptom Score (IPSS), peak flow rates (Qmax), presence of detrusor overactivity (DO), and post-voiding residual urine (PVR) from baseline to up to 6 months postoperatively.

RESULTS

A total of 132 patients were included in the analysis. Patients were divided into two groups: Group 1 included BPH patients with predominant voiding LUTS (68 Patients) while group 2 involved those with predominant storage LUTS (64 Patients). HoLEP was equally effective in management of both groups with significant improvement in urodynamics study (UDS) parameters, patient voiding and storage symptomatology, and IPSS from preoperatively to up to 6 months postoperatively with relatively low procedure complication rate and postoperative need for medication or procedure.

CONCLUSIONS

HoLEP is a safe, effective, and reliable minimally invasive surgical modality that can be relied on for BPH patients with either predominant voiding or predominant storage symptoms with relatively low procedure complicat.

摘要

目的

评估和比较钬激光前列腺剜除术(HoLEP)治疗良性前列腺增生(BPH)患者排尿或储尿下尿路症状(LUTS)的有效性和安全性。

材料与方法

回顾性分析了 2015 年 2 月至 2020 年 12 月期间在辛辛那提大学医院因排尿或储尿为主的 LUTS 接受 HoLEP 的 BPH 患者的病历,并分析了排尿症状、储尿症状、血尿、国际前列腺症状评分(IPSS)、最大尿流率(Qmax)、逼尿肌过度活动(DO)的变化和术后 6 个月的剩余尿(PVR)。

结果

共有 132 例患者纳入分析。患者分为两组:第 1 组为排尿为主的 LUTS(68 例),第 2 组为储尿为主的 LUTS(64 例)。HoLEP 在两组患者的管理中同样有效,尿动力学研究(UDS)参数、患者排尿和储尿症状以及 IPSS 均有显著改善,从术前到术后 6 个月,手术并发症发生率和术后药物或手术需求相对较低。

结论

HoLEP 是一种安全、有效、可靠的微创治疗方法,可用于治疗排尿或储尿为主的 BPH 患者,手术并发症相对较低。

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