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高强度间歇训练在冠心病患者中的获益与风险。

Benefits and Risks of High-Intensity Interval Training in Patients With Coronary Artery Disease.

机构信息

Health and Human Performance, University of Montana, Missoula, Montana; International Heart Institute, St. Patrick's Hospital, Missoula, Montana.

William Beaumont Hospital, Royal Oak, Michigan; Oakland University William Beaumont School of Medicine, Rochester, Michigan.

出版信息

Am J Cardiol. 2019 Apr 15;123(8):1370-1377. doi: 10.1016/j.amjcard.2019.01.008. Epub 2019 Jan 24.


DOI:10.1016/j.amjcard.2019.01.008
PMID:30732854
Abstract

Exercise-based cardiac rehabilitation is integral to secondary prevention in patients with coronary artery disease. Recently, the effectiveness and "superiority" of high-intensity interval training (HIIT) is a purported time-saving alternative to "traditional" moderate-intensity continuous training (MICT) in cardiac rehabilitation. The rationale for HIIT adoption is, however, not fully substantiated in the scientific literature. Established guidelines for exercise testing and training, when carefully adhered to, reduce the likelihood of triggering a cardiac event or inducing musculoskeletal injury. Clinicians should likewise consider patient risk stratification and introduce HIIT as an alternative to MICT only after patients exhibit stable and asymptomatic responses to vigorous exercise training. Although HIIT adherence appears comparable with MICT during outpatient rehabilitation, compliance drops dramatically for unsupervised exercise. Despite the enthusiasm surrounding HIIT, its main advantage over MICT appears to be short-term exercise performance outcomes and indices of vascular function. Regarding benefits to cardiovascular disease risk factor modification, management of vital signs, and measures of cardiac performance, current evidence indicates that HIIT does not outperform MICT. Long-term outcomes to HIIT are currently uncertain and logistical constraints to HIIT incorporation need additional clarification. Based on these limited findings, derived from facilities and clinicians at the forefront of cardiac rehabilitation, the routine adoption of HIIT should be viewed cautiously. In conclusion, the current review highlights numerous specific research directives that are needed before the safety and effectiveness of HIIT can be confirmed and widely adopted in patients with known or suspected coronary artery disease, especially in unsupervised, nonmedical settings.

摘要

基于运动的心脏康复是冠心病二级预防的重要组成部分。最近,高强度间歇训练(HIIT)在心脏康复中被认为是一种替代传统中等强度持续训练(MICT)的节省时间的方法,其有效性和“优越性”备受关注。然而,HIIT 的采用依据在科学文献中尚未得到充分证实。当严格遵循既定的运动测试和训练指南时,可以降低引发心脏事件或导致肌肉骨骼损伤的可能性。临床医生也应该考虑患者的风险分层,并在患者对剧烈运动训练表现出稳定和无症状的反应后,才将 HIIT 作为 MICT 的替代方法引入。尽管 HIIT 在门诊康复期间的依从性似乎与 MICT 相当,但在非监督运动时,其依从性会急剧下降。尽管 HIIT 备受关注,但与 MICT 相比,其主要优势似乎是短期运动表现结果和血管功能指标。关于对心血管疾病危险因素的改善、生命体征的管理以及心脏功能的评估,目前的证据表明 HIIT 并不优于 MICT。HIIT 的长期结果目前尚不确定,HIIT 纳入的后勤限制需要进一步澄清。基于这些有限的发现,这些发现来自心脏康复领域的前沿机构和临床医生,在可以确认 HIIT 的安全性和有效性并广泛应用于已知或疑似冠心病患者之前,应该谨慎采用 HIIT 的常规应用。总之,目前的综述强调了在 HIIT 的安全性和有效性得到确认并广泛应用于已知或疑似冠心病患者之前,需要进行许多具体的研究指导。特别是在非监督、非医疗环境中。

相似文献

[1]
Benefits and Risks of High-Intensity Interval Training in Patients With Coronary Artery Disease.

Am J Cardiol. 2019-1-24

[2]
Short-term and Long-term Feasibility, Safety, and Efficacy of High-Intensity Interval Training in Cardiac Rehabilitation: The FITR Heart Study Randomized Clinical Trial.

JAMA Cardiol. 2020-12-1

[3]
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Prog Cardiovasc Dis. 2022

[4]
High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation.

BMJ Open. 2016-11-16

[5]
High-Intensity Interval Training for Patients With Cardiovascular Disease-Is It Safe? A Systematic Review.

J Am Heart Assoc. 2018-11-6

[6]
Short-term effects of a 3-week interval training program on heart rate variability in chronic heart failure. A randomised controlled trial.

Ann Phys Rehabil Med. 2019-7-25

[7]
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Eur J Prev Cardiol. 2023-7-12

[8]
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Clin Hemorheol Microcirc. 2023

[9]
Effects of high-intensity interval training on platelet function in cardiac rehabilitation: a randomised controlled trial.

Heart. 2019-7-17

[10]
Effect of High-Intensity Interval Training on Visceral and Liver Fat in Cardiac Rehabilitation: A Randomized Controlled Trial.

Obesity (Silver Spring). 2020-5-31

引用本文的文献

[1]
Comparative effectiveness of high-intensity interval training and moderate-intensity continuous training on cardiometabolic health in patients with diabesity: a systematic review and meta-analysis of randomized controlled trials.

Diabetol Metab Syndr. 2025-8-13

[2]
High-intensity interval training improves mitochondrial function and attenuates cardiomyocytes damage in ischemia-reperfusion.

Int J Cardiol Heart Vasc. 2025-7-25

[3]
Oxidative Stress and Ultrastructural Analysis in Heart, Aorta, Skeletal Muscle and Lung of Rats Treated with N-Acetylcysteine or Rutin After Sprint Running.

J Funct Morphol Kinesiol. 2025-6-2

[4]
Biomarkers of aging: from molecules and surrogates to physiology and function.

Physiol Rev. 2025-7-1

[5]
Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR).

J Nutr Health Aging. 2025-1

[6]
Physical Activity, Cardiorespiratory Fitness, and Atherosclerotic Cardiovascular Disease: Part 2.

Pulse (Basel). 2024-10-9

[7]
Assessment of clinical depression metrics in cardiac patients using the patient health Questionnaire-9 before and after phase-II cardiac rehabilitation.

Sports Med Health Sci. 2023-9-11

[8]
The PAD-adapted 30-20-10 during Nordic walking: A new exercise training session in patients with symptomatic peripheral artery disease.

Medicine (Baltimore). 2024-6-21

[9]
Short-duration aerobic high-intensity intervals versus moderate exercise training intensity in patients with peripheral artery disease: study protocol for a randomised controlled trial (the Angiof-HIIT Study).

BMJ Open. 2024-4-17

[10]
The relationship between different exercise conditions and pericoronary inflammation as quantified by coronary CTA in coronary artery disease.

Heliyon. 2024-2-1

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