Christopher L J, Ballinger B R, Shepherd A M, Ramsay A, Crooks G
Age Ageing. 1978 May;7(2):74-82. doi: 10.1093/ageing/7.2.74.
A cross-sectional one-day survey of drug prescribing and use in elderly in-patients was carried out in Dundee hospitals. Altogether 873 patients were studied and analyses of prescribing patterns were carried out by patient categories--medical, surgical, geriatric, psychiatric and mentally subnormal--and by major drug groups. While the average number of drugs prescribed per patient on the study day was 3.3, which was not excessive, other results highlighted some possible problems of therapy, viz. the wide range of drugs used within drug groups, the common use of psychotropic drugs, dose regimes which although used in a geriatric population differed little from general adult dosages, and which sometimes involved many administrations per day. Examples were described relating to the use of nitrazepam, phenothiazines and tricyclic antidepressants.
在邓迪的医院里，对老年住院患者的药物处方和用药情况进行了为期一天的横断面调查。共研究了873名患者，并按患者类别（内科、外科、老年科、精神科和智力低下科）以及主要药物类别对处方模式进行了分析。虽然在研究日每位患者的平均处方药物数量为3.3种，不算过多，但其他结果凸显了一些可能的治疗问题，即药物组内使用的药物种类繁多、精神药物的普遍使用、剂量方案虽用于老年人群体但与一般成人剂量差别不大，且有时每天需要多次给药。文中描述了与硝西泮、吩噻嗪类药物和三环类抗抑郁药使用相关的例子。
