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本文引用的文献

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Drugs and insomnia.药物与失眠
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2
Benzodiazepine withdrawal: an unfinished story.苯二氮䓬类药物戒断:一个未完成的故事。
Br Med J (Clin Res Ed). 1984 Apr 14;288(6424):1135-40. doi: 10.1136/bmj.288.6424.1135.
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Placebo response in the evaluation of hypnotic drugs.
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Hypnotic activity of placebo in relation to severity of insomnia: a quantitative evaluation.安慰剂的催眠活性与失眠严重程度的关系:一项定量评估。
Clin Pharmacol Ther. 1967 Nov-Dec;8(6):841-8. doi: 10.1002/cpt196786841.
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A programme which led to reduction in night sedation in a major hospital.一项在一家大型医院实施的减少夜间镇静的计划。
Med J Aust. 1973 Oct 6;2(14):678-81. doi: 10.5694/j.1326-5377.1973.tb129701.x.
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Do placebos alter sleep?安慰剂会改变睡眠吗?
Br Med J. 1976 Jan 24;1(6003):195-6. doi: 10.1136/bmj.1.6003.195.
7
Toxicity of nitrazepam in the elderly: a report from the Boston Collaborative Drug Surveillance Program.硝西泮在老年人中的毒性:来自波士顿药物监测协作计划的报告。
Br J Clin Pharmacol. 1978 May;5(5):407-13. doi: 10.1111/j.1365-2125.1978.tb01646.x.
8
Drug prescribing patterns in the elderly: a cross-sectional study of in-patients.老年人的药物处方模式:一项住院患者横断面研究。
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老年住院患者对催眠药物的需求及安慰剂反应

Requests for hypnotic drugs and placebo response in elderly hospital in-patients.

作者信息

Bayer A J, Pathy M S

出版信息

Postgrad Med J. 1985 Apr;61(714):317-20. doi: 10.1136/pgmj.61.714.317.

DOI:10.1136/pgmj.61.714.317
PMID:4022861
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2418242/
Abstract

Requests for night sedation and the use of placebo as first line drug management were studied prospectively in 1174 consecutive elderly hospital in-patients. Of the 390 (33.2%) patients requesting sleeping pills in hospital, 37 were subsequently satisfied without the prescription of additional medication. A further 216 patients were entirely satisfied with a placebo capsule during all of their hospital stay. An 'active' hypnotic drug was required by only 137 patients, many of whom were noisy and disturbing other patients in the ward. Most of the active hypnotic drugs prescribed to elderly hospital patients are unnecessary and a majority of those requesting hypnotics consistently respond to placebo. There remains a need for greater education of patients, nurses and doctors in the non-pharmacological management of sleep disorders.

摘要

对1174例连续入住医院的老年患者进行了前瞻性研究,观察夜间镇静需求及使用安慰剂作为一线药物治疗的情况。在390例(33.2%)住院期间要求使用安眠药的患者中,有37例在未开具额外药物处方的情况下随后感到满意。另有216例患者在整个住院期间对安慰剂胶囊完全满意。仅137例患者需要使用“活性”催眠药物,其中许多患者吵闹并干扰病房中的其他患者。大多数开给老年住院患者的活性催眠药物是不必要的,而且大多数要求使用催眠药物的患者对安慰剂始终有反应。在睡眠障碍的非药物管理方面,仍需要对患者、护士和医生进行更多教育。