Billeter A T, Müller-Stich B P
Klinik für Allgemein‑, Viszeral- und Transplantationschirurgie, Universitätsklinik Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Deutschland.
Chirurg. 2019 Feb;90(2):157-170. doi: 10.1007/s00104-018-0786-z.
In recent years the surgical treatment of metabolic diseases has become established as an effective alternative to conservative treatment. The new S3 guidelines address these changes and give clear indications for obesity surgery. One of the core points of the new guidelines is the differentiation between obesity surgery and metabolic surgery. In obesity surgery the primary aim of treatment is weight loss whereas for metabolic indications the aim is an improvement of comorbidities independent of the body mass index (BMI). With respect to the selection of procedures sleeve gastrectomy (SG) and the traditional Roux-en-Y gastric bypass (RYGB) can be used as safe and evidence-based operative procedures. The RYGB has better metabolic effects but higher complication and reintervention rates. More recent procedures, such as the one anastomosis gastric bypass (OAGB) and single anastomosis duodeno-ileal (SADI) bypass possibly have slightly stronger metabolic effects, however, the risk of malnutrition and vitamin deficiency is higher.
近年来,代谢性疾病的外科治疗已成为保守治疗的一种有效替代方法。新的S3指南针对这些变化,明确给出了肥胖症手术的指征。新指南的核心要点之一是区分肥胖症手术和代谢手术。在肥胖症手术中,治疗的主要目的是减重,而对于代谢指征,目的是改善合并症,且与体重指数(BMI)无关。关于手术方式的选择,袖状胃切除术(SG)和传统的Roux-en-Y胃旁路术(RYGB)可作为安全且有循证依据的手术方式。RYGB具有更好的代谢效果,但并发症和再次干预率更高。更新的手术方式,如单吻合口胃旁路术(OAGB)和单吻合口十二指肠-回肠(SADI)旁路术,可能具有稍强的代谢效果,然而,营养不良和维生素缺乏的风险更高。