一名接受斜视手术的儿童疑似发生麻醉诱导的横纹肌溶解症。

A suspected case of anesthesia-induced rhabdomyolysis in a child undergoing strabismus surgery.

作者信息

Leo Anne-Marie, McVey Mark J, Iizuka Megumi, Richards Michael D

机构信息

Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.

Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Anesthesia, University of Toronto, Toronto, Ontario, Canada.

出版信息

J AAPOS. 2019 Jun;23(3):167-169. doi: 10.1016/j.jaapos.2019.01.006. Epub 2019 Feb 5.

DOI:10.1016/j.jaapos.2019.01.006

PMID:30735783

Abstract

We report a case of acute rhabdomyolysis following general anesthesia for strabismus surgery in a previously healthy 11-year-old girl. The patient received a depolarizing muscle relaxant (succinylcholine) and halogenated volatile anesthetic agent (sevoflurane) during surgery. In rare cases, these classes of drugs can trigger malignant hyperthermia (MH) or anesthesia-induced rhabdomyolysis (AIR), which can cause significant morbidity and mortality if not recognized and treated promptly. Pathophysiology, early recognition, and special considerations in strabismus patients are discussed.

摘要

我们报告了一例在全身麻醉下行斜视手术的11岁既往健康女孩发生急性横纹肌溶解症的病例。该患者在手术期间接受了去极化肌松药（琥珀胆碱）和卤化挥发性麻醉剂（七氟烷）。在罕见情况下，这类药物可引发恶性高热（MH）或麻醉诱导的横纹肌溶解症（AIR），如果未得到及时识别和治疗，可导致严重的发病率和死亡率。本文讨论了斜视患者的病理生理学、早期识别及特殊注意事项。