Centre for Pharmacoepidemiology and Drug Safety, Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Paediatric Intensive Care Unit, Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Arch Dis Child. 2019 Jun;104(6):588-595. doi: 10.1136/archdischild-2018-315981. Epub 2019 Feb 8.
To explore the factors contributing to prescribing error in paediatric intensive care units (PICUs) using a human factors approach based on Reason's theory of error causation to support planning of interventions to mitigate slips and lapses, rules-based mistakes and knowledge-based mistakes.
A hierarchical task analysis (HTA) of prescribing was conducted using documentary analysis. Eleven semistructured interviews with prescribers were conducted using vignettes and were analysed using template analysis. Contributory factors were identified through the interviews and were related to tasks in the HTA by an expert panel involving a PICU clinician, nurse and pharmacist.
Prescribing in PICU is composed of 30 subtasks. Our findings indicate that cognitive burden was the main contributory factor of prescribing error. This manifested in two ways: physical, associated with fatigue, distraction and interruption, and poor information transfer; and psychological, related to inexperience, changing workload and insufficient decision support information. Physical burden was associated with errors of omission or selection; psychological burden was linked to errors related to a lack of knowledge and/or awareness. Social control through nursing staff was the only identified control step. This control was dysfunctional at times as nurses were part of an informal mechanism to support decision making, was ineffective.
Cognitive burden on prescribers is the principal latent factor contributing to prescribing error. This research suggests that interventions relating to skill mix, and communication and presentation of information may be effective at mitigating rule and knowledge-based mistakes. Mitigating fatigue and standardising procedures may minimise slips and lapses.
运用基于Reason 错误因果理论的人为因素方法,探索导致儿科重症监护病房(PICU)处方错误的因素,为规划减轻失误、基于规则的错误和基于知识的错误的干预措施提供支持。
采用文献分析对处方制定进行分层任务分析(HTA)。通过案例分析对 11 名处方制定者进行了 11 次半结构化访谈,并采用模板分析进行分析。专家组通过访谈确定了促成因素,并通过涉及 PICU 临床医生、护士和药剂师的专家小组将促成因素与 HTA 中的任务联系起来。
PICU 的处方制定由 30 个子任务组成。我们的研究结果表明,认知负担是处方错误的主要促成因素。这表现在两个方面:身体上的,与疲劳、注意力分散和中断以及不良信息传递有关;心理上的,与经验不足、工作负荷变化和决策支持信息不足有关。身体负担与遗漏或选择错误有关;心理负担与缺乏知识和/或意识有关。通过护理人员进行的社会控制是唯一确定的控制步骤。由于护士是支持决策的非正式机制的一部分,这种控制有时会出现功能失调,而且效率低下。
处方制定者的认知负担是导致处方错误的主要潜在因素。这项研究表明,与技能组合、沟通和信息呈现相关的干预措施可能对减轻基于规则和基于知识的错误有效。减轻疲劳和标准化程序可能会最大限度地减少失误。