Chapman David, Foxcroft Roland, Dale-Harris Laura, Ronte Hanno, Bidgoli Farid, Bellary Srikanth
Monitor Deloitte, London, UK.
Social Finance Ltd., London, UK.
Diabetes Ther. 2019 Apr;10(2):575-585. doi: 10.1007/s13300-018-0548-4. Epub 2019 Feb 8.
The increasing prevalence of type 2 diabetes (T2DM) in the UK imposes a significant burden on the National Health Service (NHS). Despite the availability of effective treatments, the loss of glycaemic control over time results in significant comorbidities, including nephropathy, neuropathy and retinopathy. The cost of treating these microvascular complications has not been well documented, and this study aimed to provide an accurate assessment of the healthcare resource utilisation (HCRU) associated with managing T2DM and its complications.
This retrospective cohort study utilised electronic medical records from patients with T2DM from the Heart of England Foundation Trust (HEFT), which captures data from patients using secondary care services. Patients were diagnosed with microvascular complications based on ICD-10 or OPCS codes. HCRU over a 2-year period was based on NHS Tariffs for healthcare services for inpatient, accident and emergency, and dialysis clinic usage.
The study cohort comprised 26,629 patients with T2DM who used HEFT services during the study period, 22.6%, 20.8% and 3.1% of whom had comorbid nephropathy, retinopathy or neuropathy, respectively. While the prevalence of diabetes in the overall HEFT population was reported to be 7% in 2012, diabetes and its associated complications accounted for more than 30% of secondary care costs. Furthermore, while patients with diabetes represent only 17% of HEFT inpatients, they account for more than 20% of service usage. The economic burden of microvascular complications increased substantially with the severity of the condition, with the overall cost exceeding £70 million over the 2-year period.
This study of patients with T2DM in a typical secondary care provider in the UK showed that avoiding the progression of microvascular complications could provide substantial cost savings through targeted interventions that improve outcomes and lower resource use.
Merck Sharp & Dohme Limited.
2型糖尿病(T2DM)在英国的患病率不断上升,给国民医疗服务体系(NHS)带来了沉重负担。尽管有有效的治疗方法,但随着时间的推移,血糖控制不佳会导致严重的合并症,包括肾病、神经病变和视网膜病变。治疗这些微血管并发症的成本尚未得到充分记录,本研究旨在准确评估与管理T2DM及其并发症相关的医疗资源利用(HCRU)情况。
这项回顾性队列研究利用了来自英格兰心脏基金会信托基金(HEFT)的T2DM患者的电子病历,该病历收集了使用二级医疗服务患者的数据。根据国际疾病分类第10版(ICD-10)或英国国家卫生与临床优化研究所(OPCS)编码诊断微血管并发症。基于NHS住院、急诊和透析诊所使用医疗服务的收费标准,计算了2年期间的HCRU。
研究队列包括26629名在研究期间使用HEFT服务的T2DM患者,其中分别有22.6%、20.8%和3.1%的患者合并肾病、视网膜病变或神经病变。虽然据报道2012年HEFT总体人群中糖尿病的患病率为7%,但糖尿病及其相关并发症占二级医疗费用的30%以上。此外,虽然糖尿病患者仅占HEFT住院患者的17%,但他们占服务使用量的20%以上。微血管并发症的经济负担随着病情严重程度的增加而大幅上升,2年期间总成本超过7000万英镑。
这项针对英国一家典型二级医疗服务机构中T2DM患者的研究表明,通过有针对性的干预措施改善治疗效果并降低资源使用,避免微血管并发症的进展可以大幅节省成本。
默克夏普&多美有限公司。