Center for Perioperative Optimization, Department of Surgery, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.
Center for Perioperative Optimization, Department of Surgery, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.
Eur J Intern Med. 2019 Apr;62:54-57. doi: 10.1016/j.ejim.2019.01.013. Epub 2019 Feb 7.
Compression stockings reduce the risk of thromboembolic complications, leg edema, and edema-related pain and discomfort during long-haul flights. The aim of this study was to assess if compression stockings reduce leg edema, pain, and discomfort during a three-hour flight.
This randomized controlled trial had a paired design as participants were randomized to wear a compression stocking on one leg during a three-hour flight with the other leg acting as control. Eligibility criteria were adults aged 18-60 years living in Denmark without medical indication for wearing compression stockings during flights. The primary outcome was the change in difference of ankle circumference between legs with and without compression stocking pre- and post-flight. Secondary outcomes were changes in difference of calf circumference, pain, and discomfort pre- and post-flight. All outcomes were self-reported with measurements and questionnaires.
A total of 34 participants, median age 31 years (range 25-54), were randomized with complete follow-up. Difference in ankle circumference was median 5 mm larger post-flight compared with pre-flight (interquartile range (IQR) = 0-9, p = .001) and the corresponding change in calf circumference difference was median 5 mm (IQR = 1-12, p < .001). Ankle- and calf circumferences decreased in the leg wearing compression stocking and increased in the other leg. There was no change in difference of pain and discomfort and no adverse events.
Compression stockings reduced edema formation in young healthy passengers during a three-hour flight. Passengers experiencing edema-related discomfort during short-haul flights may benefit from wearing compression stockings during air travel.
clinicaltrials.gov: NCT03546725.
在长途飞行中，压缩袜可降低血栓栓塞并发症、腿部水肿、与水肿相关的疼痛和不适的风险。本研究旨在评估在 3 小时的飞行中，压缩袜是否可减少腿部水肿、疼痛和不适。
这是一项随机对照试验，采用配对设计，参与者被随机分配在 3 小时的飞行中在一条腿上穿压缩袜，另一条腿作为对照。纳入标准为年龄在 18-60 岁之间、居住在丹麦且无在飞行中穿压缩袜医学指征的成年人。主要结局是飞行前后穿与不穿压缩袜的腿部踝围差异的变化。次要结局是飞行前后小腿围差异、疼痛和不适的变化。所有结局均采用测量和问卷调查进行自我报告。
共有 34 名参与者，中位年龄 31 岁（范围 25-54 岁），随机分组并完成了随访。与飞行前相比，飞行后踝围差异中位数增加了 5 毫米（四分位距（IQR）=0-9，p=0.001），相应的小腿围差异中位数增加了 5 毫米（IQR=1-12，p<0.001）。穿着压缩袜的腿的踝围和小腿围缩小，而另一条腿的踝围和小腿围增加。疼痛和不适的差异没有变化，也没有不良事件。
在 3 小时的飞行中，压缩袜可减少年轻健康乘客的水肿形成。在短途飞行中经历与水肿相关的不适的乘客可能会从在航空旅行中穿压缩袜中受益。
clinicaltrials.gov：NCT03546725。
