Putra Imam Budi, Siregar Remenda, Jusuf Nelva K, Ginting Oratna, Nurhayati Raja
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sumatera Utara, General Hospital of Universitas Sumatera Utara, Medan, Indonesia.
Open Access Maced J Med Sci. 2019 Jan 8;7(1):53-55. doi: 10.3889/oamjms.2019.020. eCollection 2019 Jan 15.
Skin tag is a benign tumour of connective tissue in the skin, sessile or pedunculated, skin-like to brownish coloured and often arises in the flexure area. Etiopathogenesis of skin tag is still unclear, but one of the aetiology is associated with leptin hormone.
To determine the correlation between leptin serum level with type and number of the lesion skin tag.
This study is an observational analytic study with a cross-sectional design involving 33 skin tag patients. Diagnosis of skin tag was based on history and clinical examination; we conducted blood sampling and measurement of serum leptin level to the patients.
We found the mean serum leptin level of skin tag patients were highest on the type of lesion mixed (31.54 ± 12.85 ng/ml). The mean number of skin tag lesions was 13.6 ± 5.8 lesions. There is a very high positive correlation between serum leptin level with a number of skin tag (r = 0.86) with p < 0.05 and significant correlation between serum leptin level with the type of lesions (p = 0.037).
Serum leptin level has a very high positive correlation to a number of skin tag and significant correlation between serum leptin level with the type of lesion.
皮赘是皮肤结缔组织的一种良性肿瘤，有蒂或无蒂，颜色从皮肤色到褐色，常出现在皮肤褶皱处。皮赘的病因仍不清楚，但其中一个病因与瘦素激素有关。
确定血清瘦素水平与皮赘病变类型和数量之间的相关性。
本研究是一项采用横断面设计的观察性分析研究，涉及33例皮赘患者。皮赘的诊断基于病史和临床检查；我们对患者进行了血液采样并测量血清瘦素水平。
我们发现，皮赘患者血清瘦素水平在混合性病变类型中最高（31.54±12.85 ng/ml）。皮赘病变的平均数量为13.6±5.8个。血清瘦素水平与皮赘数量之间存在非常高的正相关性（r = 0.86），p < 0.05，血清瘦素水平与病变类型之间存在显著相关性（p = 0.037）。
血清瘦素水平与皮赘数量之间存在非常高的正相关性，血清瘦素水平与病变类型之间存在显著相关性。
