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一例假性梅格斯综合征病例。

A case of pseudo-pseudo Meigs' syndrome.

作者信息

Ahmed Omnya, Malley Tamir, Kitchen Joanne

机构信息

Rheumatology Department, Royal Berkshire Hospital, UK.

出版信息

Oxf Med Case Reports. 2019 Jan 31;2019(2):omy136. doi: 10.1093/omcr/omy136. eCollection 2019 Jan.

DOI:10.1093/omcr/omy136
PMID:30740231
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6355105/
Abstract

Here we report a case of a patient with systemic lupus erythematosus presenting with pseudo-pseudo Meigs' syndrome (PPMS): a triad of pleural effusion, ascites and raised CA-125. There have only been nine other cases reported in the literature. To our knowledge, this is the first to have an oesophago-gastro-duodenoscopy and liver biopsy as part of the diagnostic work up. Its mechanism of action is not yet fully understood but PPMS is a treatable condition that is responsive to immunosuppression. It is therefore important to consider it in patients presenting like this, where alternative diagnoses, including malignancy, have been ruled out.

摘要

在此,我们报告一例系统性红斑狼疮患者出现假性梅格斯综合征(PPMS):表现为胸腔积液、腹水和CA - 125升高的三联征。文献中仅另有9例报道。据我们所知,这是第一例将食管胃十二指肠镜检查和肝活检作为诊断检查一部分的病例。其作用机制尚未完全明确,但PPMS是一种可通过免疫抑制治疗的疾病。因此,对于出现此类症状且已排除包括恶性肿瘤在内的其他诊断的患者,考虑这一疾病很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba66/6355105/34c0fc494a0a/omy136f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba66/6355105/4db78be81933/omy136f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba66/6355105/34c0fc494a0a/omy136f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba66/6355105/4db78be81933/omy136f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba66/6355105/34c0fc494a0a/omy136f02.jpg

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引用本文的文献

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Case report: Three cases of systemic lupus erythematosus presenting primarily with massive ascites and significantly elevated CA-125 levels and a review of pseudo-pseudo Meigs' syndrome in literature.病例报告:三例以大量腹水和显著升高的 CA-125 水平为主要表现的系统性红斑狼疮,并对文献中的假性假性 Meigs 综合征进行回顾。
Front Immunol. 2024 Jul 16;15:1423631. doi: 10.3389/fimmu.2024.1423631. eCollection 2024.
2
A Case of Pseudo-Pseudo Meigs' Syndrome Despite Optimized Immunosuppressive Therapy for Systemic Lupus Erythematosus.尽管对系统性红斑狼疮进行了优化免疫抑制治疗,但仍出现假-假梅格斯综合征一例。
Cureus. 2023 Oct 9;15(10):e46753. doi: 10.7759/cureus.46753. eCollection 2023 Oct.
3

本文引用的文献

1
Systemic Lupus Erythematosus Presenting with Massive Ascites: A Case of Pseudo-Pseudo Meigs Syndrome.以大量腹水为表现的系统性红斑狼疮:一例假性梅格斯综合征病例
Case Rep Rheumatol. 2016;2016:8701763. doi: 10.1155/2016/8701763. Epub 2016 Jun 5.
2
Severe inflammation may be caused by hyperferritinemia of pseudo-pseudo Meigs' syndrome in lupus patients: two cases reports and a literature review.狼疮患者假性假性梅格斯综合征所致高血铁蛋白血症可引起严重炎症:两例病例报告及文献复习。
Clin Rheumatol. 2013 Dec;32(12):1823-6. doi: 10.1007/s10067-013-2362-8.
3
Pseudo-pseudo Meigs' syndrome in a patient with systemic lupus erythematosus.
Systemic lupus erythematosus presenting with progressive massive ascites and CA-125 elevation indicating Tjalma syndrome? A case report.
以进行性大量腹水和CA-125升高为表现的系统性红斑狼疮提示Tjalma综合征?一例病例报告。
World J Clin Cases. 2022 Sep 16;10(26):9447-9453. doi: 10.12998/wjcc.v10.i26.9447.
4
A Rare Case of Pseudo-Meigs' Syndrome With Ovarian Metastasis Presenting as Meigs' Syndrome.一例罕见的伴有卵巢转移的假性梅格斯综合征表现为梅格斯综合征。
Cureus. 2020 Oct 18;12(10):e11022. doi: 10.7759/cureus.11022.
5
Giant ovarian fibroma with associated Meigs syndrome in low resources setting.资源匮乏地区伴发梅格斯综合征的巨大卵巢纤维瘤
J Surg Case Rep. 2019 Apr 30;2019(4):rjz143. doi: 10.1093/jscr/rjz143. eCollection 2019 Apr.
系统性红斑狼疮患者的假性假性梅格斯综合征。
Lupus. 2012 Nov;21(13):1463-6. doi: 10.1177/0961203312461291. Epub 2012 Sep 14.
4
A rare form of SLE: pseudo-pseudo meigs syndrome and hydrocephalus.一种罕见的系统性红斑狼疮形式:假性梅格斯综合征与脑积水。
Rheumatol Int. 2013 Aug;33(8):2175-6. doi: 10.1007/s00296-012-2420-6. Epub 2012 Mar 27.
5
Pseudo-pseudo Meigs syndrome developed under the leflunomide therapy.左氟米特治疗下出现的假性假性梅格斯综合征。
Rheumatol Int. 2011 Apr;31(4):521-3. doi: 10.1007/s00296-009-1190-2. Epub 2009 Oct 21.
6
Tjalma's or pseudo-pseudo-Meigs' syndrome: a case report.恰尔马氏或假-假-梅格斯综合征:一例报告
Clin Exp Dermatol. 2008 May;33(3):363-4. doi: 10.1111/j.1365-2230.2007.02665.x.
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Pseudo-pseudo Meigs' syndrome.假性梅格斯综合征。
Lancet. 2005 Nov 5;366(9497):1672. doi: 10.1016/S0140-6736(05)67666-0.
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Ascites, pleural effusion, and CA 125 elevation in an SLE patient, either a Tjalma syndrome or, due to the migrated Filshie clips, a pseudo-Meigs syndrome.一名系统性红斑狼疮患者出现腹水、胸腔积液和CA 125升高,可能是Tjalma综合征,也可能是由于Filshie夹移位导致的假性梅格斯综合征。
Gynecol Oncol. 2005 Apr;97(1):288-91. doi: 10.1016/j.ygyno.2004.12.022.