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How to prevent inadvertent emergency anticoagulation in acute type A aortic dissection: when in doubt, don't.如何预防急性A型主动脉夹层的意外紧急抗凝:如有疑问,请勿抗凝。
Cardiovasc Diagn Ther. 2018 Dec;8(6):805-810. doi: 10.21037/cdt.2018.10.13.
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Aortic dissection patients mimic acute coronary syndrome with preoperative antiplatelet therapy.主动脉夹层患者在术前接受抗血小板治疗时会表现出类似急性冠状动脉综合征的症状。
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The utility of the aortic dissection team: outcomes and insights after a decade of experience.主动脉夹层治疗团队的作用:十年经验后的结果与见解。
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Anticoagulation in Acute Coronary Syndrome-State of the Art.急性冠状动脉综合征的抗凝治疗——最新进展。
Prog Cardiovasc Dis. 2018 Jan-Feb;60(4-5):508-513. doi: 10.1016/j.pcad.2018.01.004. Epub 2018 Jan 13.
2
Warfarin anticoagulation in acute type A aortic dissection survivors (WATAS).急性A型主动脉夹层幸存者的华法林抗凝治疗(WATAS)
Cardiovasc Diagn Ther. 2017 Dec;7(6):559-571. doi: 10.21037/cdt.2017.07.01.
3
Surgery for acute type A aortic dissection on oral anticoagulants: Being the dispatcher of a 911 call.接受口服抗凝剂治疗的急性A型主动脉夹层手术:作为911急救电话的调度员
J Thorac Cardiovasc Surg. 2018 Jan;155(1):e5-e6. doi: 10.1016/j.jtcvs.2017.09.028. Epub 2017 Sep 18.
4
Delayed surgery in patients with acute type A aortic dissection who are receiving novel oral anticoagulants.正在接受新型口服抗凝剂治疗的急性A型主动脉夹层患者的延迟手术
J Thorac Cardiovasc Surg. 2018 Jan;155(1):e1-e4. doi: 10.1016/j.jtcvs.2017.08.021. Epub 2017 Aug 24.
5
Painless Aortic Dissection-Diagnostic Dilemma With Fatal Outcomes: What Do We Learn?无痛性主动脉夹层——伴有致命后果的诊断难题:我们能学到什么?
J Investig Med High Impact Case Rep. 2017 Jul 31;5(3):2324709617721252. doi: 10.1177/2324709617721252. eCollection 2017 Jul-Sep.
6
Insight into the incidence of acute aortic dissection in the German region of Berlin and Brandenburg.对德国柏林和勃兰登堡地区急性主动脉夹层发病率的洞察。
Int J Cardiol. 2017 Aug 15;241:326-329. doi: 10.1016/j.ijcard.2017.05.024. Epub 2017 May 6.
7
The incidence and mortality of acute thoracic aortic dissection: results from a whole nation study.急性胸主动脉夹层的发病率和死亡率:一项全国性研究的结果
Eur J Cardiothorac Surg. 2016 Dec;50(6):1111-1117. doi: 10.1093/ejcts/ezw235. Epub 2016 Jun 22.
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Diagnosis of Aortic Dissection in Emergency Department Patients is Rare.急诊科患者中主动脉夹层的诊断很少见。
West J Emerg Med. 2015 Sep;16(5):629-31. doi: 10.5811/westjem.2015.6.25752. Epub 2015 Oct 20.
9
Management of acute aortic dissection.急性主动脉夹层的处理。
Lancet. 2015 Feb 28;385(9970):800-11. doi: 10.1016/S0140-6736(14)61005-9. Epub 2015 Feb 6.
10
Aortic dissection with concomitant acute myocardial infarction: From diagnosis to management.主动脉夹层伴发急性心肌梗死:从诊断到治疗
J Emerg Trauma Shock. 2011 Apr;4(2):273-8. doi: 10.4103/0974-2700.82221.

如何预防急性A型主动脉夹层的意外紧急抗凝:如有疑问,请勿抗凝。

How to prevent inadvertent emergency anticoagulation in acute type A aortic dissection: when in doubt, don't.

作者信息

Zschaler Silke, Schmidt Gerard, Kukucka Marian, Syrmas Georg, Zaschke Lisa, Kurz Stephan Dominik

机构信息

Institute for Anesthesiology, Deutsches Herzzentrum Berlin, Berlin, Germany.

Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany.

出版信息

Cardiovasc Diagn Ther. 2018 Dec;8(6):805-810. doi: 10.21037/cdt.2018.10.13.

DOI:10.21037/cdt.2018.10.13
PMID:30740328
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6331368/
Abstract

Inadvertent emergency anticoagulation in patients with acute type A aortic dissection (ATAAD) has been sparsely reported. There are case reports bringing this potential critical incident to attention, however, little is known about the number of undetected and unreported cases. We approach this issue based on a case report of inadvertent emergency anticoagulation in ATAAD and attempt to shed light on aspects that may have contributed to the critical incident: The challenge of distinguishing an ATAAD from an acute coronary syndrome (ACS) and the potential underestimation of incidents of ATAAD. We also discuss errors and biases in medical decision making, and provide suggestions that may help raise awareness of how ATAAD can be mimicking ACS in clinical practice.

摘要

急性A型主动脉夹层(ATAAD)患者的意外紧急抗凝情况鲜有报道。虽有病例报告引起了人们对这一潜在严重事件的关注,但对于未被发现和未报告的病例数量却知之甚少。我们基于一例ATAAD意外紧急抗凝的病例报告来探讨这个问题,并试图阐明可能导致这一严重事件的因素:区分ATAAD与急性冠状动脉综合征(ACS)的挑战以及ATAAD事件可能被低估的情况。我们还讨论了医疗决策中的错误和偏差,并提出了一些建议,可能有助于提高人们对ATAAD在临床实践中如何模仿ACS的认识。