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全主动脉修复:急性A型主动脉夹层治疗的新范式

Total aortic repair: the new paradigm in the treatment of acute type A aortic dissection.

作者信息

Matalanis George, Perera Nisal K, Galvin Sean D

机构信息

1 Department of Cardiac Surgery, The Austin Hospital, Heidelberg, Australia ; 2 Department of Cardiothoracic Surgery, Wellington Regional Hospital, Wellington, New Zealand.

出版信息

Ann Cardiothorac Surg. 2016 May;5(3):216-21. doi: 10.21037/acs.2016.05.02.

Abstract

The surgical management of acute type A aortic dissection (ATAAD) is in a period of rapid evolution. Understanding the complex physiology and anatomy of both acute and chronic dissection has been enhanced by the ready availability of state of the art imaging techniques. Technical advances in the intraoperative monitoring of organ perfusion, together with adjuncts to limit organ injury and increasing sophistication in open and endovascular surgery have led to a major reduction in both perioperative morbidity and mortality. In many centers, there has been a transition in mindset and surgical approach away from a purely central aortic operation focusing on the ascending aorta and a 'live to fight another day' philosophy. The current more global perspective recognizes the importance of aortic valve function, malperfusion, false lumen (FL) patency and the potential for future complex aneurysm development. The time is now right to transition into the next phase of sophistication in the management of ATAAD with the aim of achieving not only a safe acute operation, but to either entirely prevent chronic complications or to greatly simplify their management by the creation of an anatomical situation that facilitates future endovascular intervention in place of complex re-do surgery. We present our view on the evolution of surgery for ATAAD leading to our current technique of Branch First Arch replacement and Total Aortic Repair, which not only provides a safe immediate operation, but also offers the hope of a simplified future management if not a total cure for the pathology.

摘要

急性A型主动脉夹层(ATAAD)的外科治疗正处于快速发展阶段。先进成像技术的广泛应用加深了人们对急慢性夹层复杂生理和解剖结构的理解。术中器官灌注监测技术的进步,以及限制器官损伤的辅助手段和开放手术与血管腔内手术技术的日益成熟,已使围手术期发病率和死亡率大幅降低。在许多中心,思维模式和手术方法已从单纯关注升主动脉的中央主动脉手术及“留得青山在,不怕没柴烧”的理念发生转变。当前更全面的观点认识到主动脉瓣功能、灌注不良、假腔通畅以及未来发生复杂动脉瘤的可能性的重要性。现在正是将ATAAD治疗提升到下一阶段精细化水平的时候,目标不仅是实现安全的急性手术,还要通过构建有利于未来血管腔内干预而非复杂再次手术的解剖结构,完全预防慢性并发症或极大简化其管理。我们阐述了ATAAD手术的发展历程以及由此形成的我们目前的分支优先主动脉弓置换和全主动脉修复技术,该技术不仅能提供安全的即刻手术,还为未来简化治疗(即便不能完全治愈该病)带来了希望。

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