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非小细胞肺癌微创外科治疗进展。

Updates on Minimally Invasive Surgery in Non-Small Cell Lung Cancer.

机构信息

Department of Thoracic Surgery, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.

出版信息

Curr Treat Options Oncol. 2019 Feb 11;20(2):16. doi: 10.1007/s11864-019-0614-9.

Abstract

Video-assisted thoracic surgery (VATS) has become widely used since the 1990s and has become a standard treatment approach mainly for early-stage non-small cell lung cancer. The few randomized controlled trials providing evidence of the effectiveness of VATS lobectomy at present are supported by a large number of propensity-matched studies, several high-quality meta-analyses, and outcome studies. These studies provide comprehensive data demonstrating the lower morbidity, shorter chest tube duration, and shorter hospital stay of VATS than thoracotomy during the postoperative course. Moreover, VATS shows equivalent oncological outcome as thoracotomy and therefore should be performed for lobectomy as much as possible. Importantly, VATS has recently been applied to advanced cases and previously contraindicated complex procedures such as bronchoplasty and chest wall resection. Attention has also been paid to reduced port surgery performed by frontier surgeons. Thus, the indications of VATS have seen a significant expansion. This major development logically negates any hesitation to change to the VATS technique as any doubt will likely constrain its wider applications. Preparation of scientific learning environments is necessary and should be actively pursued to adopt new skills instead of debating between the choice of "VATS or open."

摘要

自 20 世纪 90 年代以来,电视辅助胸腔镜手术(VATS)得到了广泛应用,并已成为早期非小细胞肺癌的主要标准治疗方法。目前,为数不多的提供 VATS 肺叶切除术有效性证据的随机对照试验得到了大量倾向匹配研究、几项高质量荟萃分析和结果研究的支持。这些研究提供了全面的数据,表明 VATS 在术后过程中的发病率较低、胸腔引流管持续时间较短和住院时间较短。此外,VATS 的肿瘤学结果与开胸手术相当,因此应尽可能进行肺叶切除术。重要的是,VATS 最近已应用于晚期病例和以前被认为是禁忌的复杂手术,如支气管成形术和胸壁切除术。人们还关注到前沿外科医生进行的减少端口手术。因此,VATS 的适应证有了显著的扩大。这一重大发展从逻辑上否定了对 VATS 技术的任何犹豫,因为任何疑虑都可能限制其更广泛的应用。科学学习环境的准备是必要的,应该积极采用新技术,而不是在“VATS 还是开胸”之间进行选择。

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