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《有机化学家电喷雾质谱结构解析指南》

An Organic Chemist's Guide to Electrospray Mass Spectrometric Structure Elucidation.

机构信息

Hevesy György PhD School of Chemistry, ELTE Eötvös Loránd University, Pázmány Péter sétány 1/A, 1117 Budapest, Hungary.

Department of Analytical Chemistry, ELTE Eötvös Loránd University, Pázmány Péter sétány 1/A, 1117 Budapest, Hungary.

出版信息

Molecules. 2019 Feb 10;24(3):611. doi: 10.3390/molecules24030611.

DOI:10.3390/molecules24030611
PMID:30744143
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6384780/
Abstract

Tandem mass spectrometry is an important tool for structure elucidation of natural and synthetic organic products. Fragmentation of odd electron ions (OE⁺) generated by electron ionization (EI) was extensively studied in the last few decades, however there are only a few systematic reviews available concerning the fragmentation of even-electron ions (EE⁺/EE) produced by the currently most common ionization techniques, electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI). This review summarizes the most important features of tandem mass spectra generated by collision-induced dissociation fragmentation and presents didactic examples for the unexperienced users.

摘要

串联质谱是阐明天然和合成有机产物结构的重要工具。在过去几十年中，人们广泛研究了电子电离（EI）产生的奇数电子离子（OE⁺）的碎裂，然而，关于目前最常用的两种电离技术——电喷雾电离（ESI）和大气压化学电离（APCI）产生的偶数电子离子（EE⁺/EE）碎裂的系统综述却很少。本文总结了由碰撞诱导解离碎裂产生的串联质谱的最重要特征，并为没有经验的用户提供了教学示例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6f6/6384780/c05c22a9b864/molecules-24-00611-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6f6/6384780/360ad484a458/molecules-24-00611-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6f6/6384780/8696a49e9377/molecules-24-00611-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6f6/6384780/7b365c8681a5/molecules-24-00611-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6f6/6384780/22c7a0a3cc96/molecules-24-00611-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6f6/6384780/a0dd9e2a6d75/molecules-24-00611-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6f6/6384780/396260653844/molecules-24-00611-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6f6/6384780/c05c22a9b864/molecules-24-00611-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6f6/6384780/360ad484a458/molecules-24-00611-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6f6/6384780/8696a49e9377/molecules-24-00611-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6f6/6384780/7b365c8681a5/molecules-24-00611-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6f6/6384780/22c7a0a3cc96/molecules-24-00611-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6f6/6384780/a0dd9e2a6d75/molecules-24-00611-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6f6/6384780/396260653844/molecules-24-00611-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6f6/6384780/c05c22a9b864/molecules-24-00611-g006.jpg

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