INRA-UCA UMR 1095 Génétique Diversité et Ecophysiologie des Céréales, 63100, Clermont-Ferrand, France.
Laboratoire d'Anthropobiologie Moléculaire et d'Imagerie de Synthèse, CNRS UMR 5288, allées Jules Guesde, Bâtiment A, 31000, Toulouse, France.
Genome Biol. 2019 Feb 11;20(1):29. doi: 10.1186/s13059-019-1627-1.
How contemporary plant genomes originated and evolved is a fascinating question. One approach uses reference genomes from extant species to reconstruct the sequence and structure of their common ancestors over deep timescales. A second approach focuses on the direct identification of genomic changes at a shorter timescale by sequencing ancient DNA preserved in subfossil remains. Merged within the nascent field of paleogenomics, these complementary approaches provide insights into the evolutionary forces that shaped the organization and regulation of modern genomes and open novel perspectives in fostering genetic gain in breeding programs and establishing tools to predict future population changes in response to anthropogenic pressure and global warming.
当代植物基因组是如何起源和进化的是一个引人入胜的问题。一种方法是利用现存物种的参考基因组,在长时间尺度上重建它们共同祖先的序列和结构。另一种方法侧重于通过对保存在亚化石遗迹中的古代 DNA 进行测序,直接鉴定较短时间尺度上的基因组变化。这两种方法在新兴的古基因组学领域中融合在一起,为我们深入了解塑造现代基因组组织和调控的进化力量提供了线索,并为在育种计划中促进遗传增益和建立工具以预测未来人口变化以应对人为压力和全球变暖提供了新的视角。