Shan Xueling, Pan Yuting, Chen Xiaohui, Wang Wenchang, Chen Zhidong
Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, School of Petrochemical Engineering, Changzhou University.
School of Chemistry and Material Engineering, Changzhou Vocational Institute of Engineering.
Anal Sci. 2019 Jun 10;35(6):639-644. doi: 10.2116/analsci.18P572. Epub 2019 Feb 8.
A novel electrochemiluminescence (ECL) sensor for detection of brilliant blue FCF (BB) has been developed using Ru@Zn-MOF/nafion modified GCE (glass carbon electrode) in this research. Different from conventional method for usage of Ru(bpy) in solution-phase, Ru(bpy) here was immobilized on a zinc-metal-organic-framework (Zn-MOF). After adding BB, a significant quenching phenomenon of ECL intensity was observed. The behavior of BB on the quenching effect of Ru(bpy)/Zn-MOF in different conditions was investigated thoroughly and the detection limit was achieved to 2.5 × 10 M in an optimized condition. Furthermore, the interference of some conventional ions and amino acids to the detection of BB was also investigated. Additionally, the composite showed a good effect on the detection of BB in commercial samples. The proposed sensor provided a promising platform for food safety analysis, environmental monitoring and clinical testing.
本研究利用Ru@Zn-MOF/nafion修饰的玻碳电极（GCE）开发了一种用于检测亮蓝FCF（BB）的新型电化学发光（ECL）传感器。与传统的在溶液相中使用Ru(bpy)的方法不同，此处的Ru(bpy)被固定在锌基金属有机框架（Zn-MOF）上。加入BB后，观察到ECL强度有明显的猝灭现象。深入研究了BB在不同条件下对Ru(bpy)/Zn-MOF猝灭效应的行为，在优化条件下检测限达到2.5×10 M。此外，还研究了一些常规离子和氨基酸对BB检测的干扰。此外，该复合材料对商业样品中BB的检测显示出良好的效果。所提出的传感器为食品安全分析、环境监测和临床检测提供了一个有前景的平台。
