Rosas Laura, Rao Kavya, McGough Christine, Becker Ashley
McGovern Medical School, University of Texas Health Science Center, Houston, TX, USA.
Division of Child Neurology, Department of Pediatrics, University of Texas Health Science Center, Houston, TX, USA.
Child Neurol Open. 2019 Jan 31;6:2329048X19826480. doi: 10.1177/2329048X19826480. eCollection 2019.
The authors describe a 12-year-old girl with an atypical presentation of encephalitis. She presented with fever and altered mental status and developed flaccid paralysis of her left upper extremity a day later. An electroencephalogram showed slowing over her right hemisphere. She had mild leukocytosis and bandemia, but her imaging and cerebrospinal studies were unrevealing. After five days, her symptoms resolved and she was discharged home on doxycycline due to suspicion for encephalitis. The patient admitted to playing with a kitten two months prior, but she lacked the classic regional lymphadenopathy. titers were sent during her hospitalization and returned positive after her discharge. Cat scratch disease neurologic manifestations are uncommon, with hemiplegia being exceedingly rare. This case illustrates that focal neurologic signs may develop during cat scratch disease infection and suggests that cat scratch disease encephalitis should be considered during evaluation of a pediatric patient with acute flaccid paralysis.
作者描述了一名12岁患有非典型脑炎表现的女孩。她最初表现为发热和精神状态改变,一天后出现左上肢弛缓性麻痹。脑电图显示右半球活动减慢。她有轻度白细胞增多和杆状核细胞增多,但影像学和脑脊液检查均无异常发现。五天后,她的症状缓解,因疑似脑炎出院时服用强力霉素。该患者承认两个月前曾与一只小猫玩耍,但她没有典型的局部淋巴结病。住院期间进行了抗体滴度检测,出院后结果呈阳性。猫抓病的神经系统表现并不常见,偏瘫极为罕见。该病例表明,猫抓病感染期间可能出现局灶性神经体征,提示在评估患有急性弛缓性麻痹的儿科患者时应考虑猫抓病性脑炎。