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特定因素可预测憩室炎手术患者进行急诊和紧急结肠切除术的风险。

Specific Factors Predict the Risk for Urgent and Emergent Colectomy in Patients Undergoing Surgery for Diverticulitis.

作者信息

Valizadeh Neda, Suradkar Kunal, Kiran Ravi P

出版信息

Am Surg. 2018 Nov 1;84(11):1781-1786.

Abstract

The aim of this study was to identify preoperative characteristics that may determine the need for emergency surgery for diverticulitis and assess postoperative outcomes for these patients when compared with elective surgery. All patients included in the ACS-NSQIP-targeted colectomy database from 2012 to 2013 who underwent colectomy with an underlying diagnosis of diverticulitis were included. Preoperative characteristics and 30-day postoperative outcomes were evaluated for patients who underwent elective emergent/urgent surgery using univariable and multivariable analyses. Of 8708 patients with diverticular disease, 28.1 per cent underwent emergent/urgent colectomy. Patients who underwent emergent/urgent colectomy had greater preoperative steroid use, diabetes mellitus, disseminated cancer, chronic renal failure, hypertension, chronic heart failure, chronic liver disease, COPD, and dependent functional health status ( < 0001). There were more patients with age >65 years ( < 0001), smoking history ( < 0.05), and BMI < 18.5 kg/m² ( < 0001) in the emergent/urgent colectomy group. After performing multivariable analysis, preoperative steroid use, weight loss >10 per cent, BMI < 18 kg/m², smoking, age > 65, and comorbid conditions were associated with a higher rate of emergent/urgent surgery. Mortality (5.2% 0.2%) and infectious and noninfectious complications were higher after nonelective colectomy. Emergent/urgent colectomy was also associated with longer hospital stay and reoperation. Emergency and urgent colectomy for diverticulitis is associated with significantly worse outcomes than after elective surgery, and patients with comorbid conditions who develop attacks of diverticulitis may in fact be the population that might best benefit from a lower threshold for an elective colectomy.

摘要

本研究的目的是确定可能决定憩室炎患者是否需要急诊手术的术前特征,并与择期手术患者相比,评估这些患者的术后结局。纳入2012年至2013年美国外科医师学会国家外科质量改进计划(ACS-NSQIP)靶向结肠切除术数据库中所有因憩室炎接受结肠切除术的患者。使用单变量和多变量分析评估接受择期、急诊/紧急手术患者的术前特征和术后30天结局。在8708例憩室病患者中,28.1%接受了急诊/紧急结肠切除术。接受急诊/紧急结肠切除术的患者术前使用类固醇、患有糖尿病、播散性癌症、慢性肾衰竭、高血压、慢性心力衰竭、慢性肝病、慢性阻塞性肺疾病(COPD)以及依赖性功能健康状况的比例更高(P<0.0001)。急诊/紧急结肠切除术组中年龄>65岁(P<0.0001)、有吸烟史(P<0.05)和体重指数(BMI)<18.5kg/m²(P<0.0001)的患者更多。进行多变量分析后,术前使用类固醇、体重减轻>10%、BMI<18kg/m²、吸烟、年龄>65岁以及合并症与急诊/紧急手术发生率较高相关。非择期结肠切除术后死亡率(5.2%±0.2%)以及感染性和非感染性并发症发生率更高。急诊/紧急结肠切除术还与住院时间延长和再次手术相关。憩室炎的急诊和紧急结肠切除术与择期手术后的结局相比明显更差,患有合并症且发生憩室炎发作的患者实际上可能是最能从较低的择期结肠切除术阈值中获益的人群。

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