Sanaiha Yas, Bailey Katherine L, Aguayo Esteban, Seo Young-Ji, Dobaria Vishal, Lin Anne Y, Benharash Peyman
Division of Cardiac Surgery, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Am Surg. 2018 Oct 1;84(10):1560-1564.
Disparities in the incidence of pulmonary embolism (PE) based on racial and socioeconomic factors remain ill-defined. The present study evaluated the impact of race and hospital characteristics on rates of PE for all adult colectomy patients in the 2005 to 2014 Nationwide Inpatient Sample. Hospitals were designated as high-burden hospitals (HBHs) or low-burden hospitals of underinsured payers. Chi-squared tests of trend and multivariable regression adjusting for patient and hospital characteristics were performed. Of the 2,737,977 adult patients who underwent colectomy in the study period, 79 per cent were White, 10 per cent Black, and 7 per cent Hispanic. The annual rate of PE increased from 0.6 per cent in 2005 to 0.95 per cent in 2014 ( < 0.0001). Black patients had significantly higher incidence of PE than Whites (1.5% 0.9%, < 0.001) and Hispanics (1.5% 0.8%, < 0.001). Colectomy at HBHs was also associated with significantly higher rates of PE (1% 0.86%, < 0.001). After adjusting for baseline differences, colectomy at HBHs (odds ratio 1.14, 95% confidence interval 1.02-1.27, = 0.02) and Black race (odds ratio 1.4, 95% confidence interval 1.26-1.66, < 0.001) were independent predictors of PE. In this national study of colectomy patients, Black patients experienced a disproportionate burden of postoperative PE. Further investigation into the causes and prevention of PE in vulnerable populations may identify targets for surgical quality improvement.
基于种族和社会经济因素的肺栓塞(PE)发病率差异仍不明确。本研究评估了种族和医院特征对2005年至2014年全国住院患者样本中所有成年结肠切除术患者PE发生率的影响。医院被指定为高负担医院(HBHs)或未参保支付者的低负担医院。进行了趋势卡方检验和针对患者及医院特征进行调整的多变量回归分析。在研究期间接受结肠切除术的2737977名成年患者中,79%为白人,10%为黑人,7%为西班牙裔。PE的年发生率从2005年的0.6%增至2014年的0.95%(<0.0001)。黑人患者的PE发生率显著高于白人(1.5%对0.9%,<0.001)和西班牙裔(1.5%对0.8%,<0.001)。在高负担医院进行结肠切除术也与显著更高的PE发生率相关(1%对0.86%,<0.001)。在调整基线差异后,在高负担医院进行结肠切除术(优势比1.14,95%置信区间1.02 - 1.27,P = 0.02)和黑人种族(优势比1.4,95%置信区间1.26 - 1.66,<0.001)是PE的独立预测因素。在这项针对结肠切除术患者的全国性研究中,黑人患者术后PE负担过重。对弱势群体中PE的原因和预防进行进一步调查可能会确定手术质量改进的目标。