Baier R, Puppel H
Dtsch Med Wochenschr. 1978 Jul 7;103(27):1112-6. doi: 10.1055/s-0028-1129211.
The sensitivity against 5 antimycotics was examined with 353 yeast strains of 13 species from clinical material. The tests were carried out by means of the disc diffusion test on Bacto yeast morphology agar under standardized conditions. 33 (6.3%) of the isolates were resistant against 5-fluorocytosine, 11 (2.1%) strains showed no sensitivity against the imidazolyl antimycotics clotrimazole or miconazole. The resistant strains belonged to the species Candida albicans and Candida tropicalis. All of the isolates were sensitive to the polyene antimycotics nystatin and pimaricin (natamycin).
用来自临床材料的13个种的353株酵母菌株检测了对5种抗真菌药的敏感性。试验在标准化条件下,采用纸片扩散法在细菌酵母形态学琼脂上进行。33株(6.3%)分离株对5-氟胞嘧啶耐药,11株(2.1%)菌株对咪唑类抗真菌药克霉唑或咪康唑不敏感。耐药菌株属于白色念珠菌和热带念珠菌。所有分离株对多烯类抗真菌药制霉菌素和匹马霉素(游霉素)敏感。